Clinical Study

Predictors of Neurological and Functional Recovery in Patients with Moderate to Severe Ischemic Stroke: The EPICA Study

Table 2

Neurological and Functional Assessments at Baseline, month 1 and month 3.

AssessmentsBaseline (D0)Month 1Month 3

NIHSS
 Mean (SD)10.8 (5.0)7.4 (4.9)5.7 (4.3)1
 Median (IQR)10 (7 - 15)7 (4 -10)5 (2 - 9)2
  ; (%)35 (26.7)15 (11.5)6 (4.8)
mRS
 Median (IQR)4 (3-5)3 (3-4)3 (2-4)3
 0; (%)2 (1.5)2 (1.5)4 (3.1)4
 13 (2.3)4 (3.1)11 (8.4)
 28 (6.1)22 (16.8)41 (31.3)
 330 (22.9)41 (31.3)35 (26.7)
 445 (34.4)40 (30.5)25 (19.1)
 543 (32.8)22 (16.8)10 (7.6)
 60 (0.0)0 (0.0)1 (0.8)
BI
 Mean (SD)45.1 (29.2)58.9 (28.17)69.9 (27.7)1
 Median (IQR)40 (20-70)55 (40-85)80 (50-95)
 95-1008 (6.3)17 (13.4)31 (25.4)
 65-9031 (24.4)44 (34.6)50 (41.0)
 ≤6088 (69.3)65 (51.2)41 (33.6)
GCS
 Mean (SD)14.4 (1.29)14.6 (1.02)14.8 (1.18)1
MEC
 Mean (SD)29. 4 (7.1)31.4 (5. 7)31.3 (6. 2)1
 Median (IQR)32 (28-35)34 (30-35)35 (30-35)

D0 versus month 3. 1 Student t-test for repeated measures. 2 McNemar test. 3 Wilcoxon test. 4 Mann-Whitney U test for ordinal analysis. NIHSS: National Institute of Health Stroke Scale; mRS: modified Rankin Scale; BI: Barthel index; GCS: Glasgow Coma Scale; MEC: Mini-Examen Cognoscitivo de Lobo; SD: standard deviation; IQR: interquartile range.