Research Article

Implications of the Presence of Hyperdense Middle Cerebral Artery Sign in Determining the Subtypes of Stroke Etiology

Table 1

Baseline characteristics of patients.

CharacteristicsTotal ()Cardioembolism ()LAA ()Others () value

Age (years)—mean (±SD)68 (15.2)71.8 (14.1)68.6 (13.3)60.3 (18.1)0.016
Male—no. (%)52 (52.5)27 (46.6)14 (63.6)11 (57.9)0.343
Body weight (kg)—mean (±SD)61.2 (14.8)59.6 (14.8)67.2 (13.2)59.0 (15.2)0.091
Risk factors
 Hypertension—no. (%)61 (61.6)37 (63.8)19 (86.4)5 (26.3)<0.001
 Hypercholesterolemia—no. (%)42 (42.4)27 (46.6)10 (45.5)5 (26.3)0.294
 Diabetes—no. (%)21 (21.2)14 (24.1)6 (27.3)1 (5.3)0.145
 Atrial fibrillation—no. (%)29 (29.3)26 (44.8)1 (4.6)2 (10.5)<0.001
 Smoker—no. (%)46 (46.5)23 (39.7)14 (63.6)9 (47.4)0.158
 Prior stroke or TIA—no. (%)12 (12.1)9 (15.5)2 (9.1)1 (5.3)0.579
Thrombolysis
 Admission mRS—median (IQR)4 (4-5)4 (4-5)4 (3-4)4 (4-5)0.215
 ONT (minutes)—median (IQR)141 (110-192)140 (110-189)152.5 (113-225)124 (97-192)0.528
 DNT (minutes)—median (IQR)52 (46-60)52 (48-60)48 (38-53)57.5 (50.5-69.5)0.008
 ODT (minutes)—median (IQR)87 (56-135)87 (56-130)105 (64-190)74.5 (34-105.5)0.117
 Baseline SBP (mmHg)—median (IQR)144 (130-167)138 (124-170)148 (132-167)148 (134-162)0.401
 Baseline DBP (mmHg)—median (IQR)81 (69-97)80.5 (69-100)86.5 (68-96)81 (74-92)0.987
 Baseline NIHSS—median (IQR)14 (8-20)16.5 (10-21)11.5 (7-13)8 (8-17)0.021
 Baseline glucose (mg/dL)—median (IQR)121 (102-155)123.5 (105-155)128 (103-215)113 (96-140)0.283
 ASPECTS—median (IQR)9 (8-10)9 (8-10)9 (9-10)9 (8-10)0.227

ASPECTS: Alberta Stroke Program Early CT Score; DBP: diastolic blood pressure; DNT: door-to-needle time; IQR: interquartile range; LAA: large-artery atherosclerosis; mRS: modified Rankin Scale; NIHSS: National Institute of Health Stroke Scale; ODT: onset-to-door time; ONT: onset-to-needle time; SBP: systolic blood pressure; SD: standard deviation; TIA: transient ischemic attack.