Research Article

Insight on the Genetics of Atrial Fibrillation in Puerto Rican Hispanics

Table 3

Linear regression analysis of the association between each relevant SNPs and AF in Puerto Rican Hispanics. SNPs were chosen from previous reports that showed a significant association with AF in Europeans.

SNPsFrequency (, %)OR atrial fibrillation
01212
OR95% CIOR95% CI

rs2834618314 (56.577%)203 (36.577%)38 (6.847%)1.16(1.079, 1.238)1.56(1.347, 1.803)
rs2040862303 (54.595%)208 (37.477%)44 (7.928%)1.09(1.017, 1.169)1.49(1.258, 1.775)
rs6462079255 (45.946%)237 (42.703%)63 (11.351%)1.10(1.040, 1.168)1.24(1.119, 1.382)
rs7508211 (38.018%)237 (42.703%)107 (19.279%)1.07(1.010, 1.134)1.18(1.063, 1.307)
rs284277195 (35.135%)265 (47.748%)95 (17.117%)0.89(0.842, 0.949)0.83(0.764, 0.896)
rs12426679195 (35.135%)265 (47.748%)95 (17.117%)0.92(0.864, 0.970)0.88(0.803, 0.962)
rs10458660435 (78.378%)101 (18.198%)19 (3.423%)1.06(1.003, 1.123)0.97(0.852, 1.098)
rs4073778269 (48.468%)226 (40.721%)60 (10.811%)0.95(0.893, 1.007)0.91(0.834, 0.982)
rs883079199 (35.856%)266 (47.928%)90 (16.216%)0.95(0.899, 1.012)0.95(0.868, 1.036)
rs10873298269 (48.468%)226 (40.721%)60 (10.811%)0.95(0.894, 1.010)0.95(0.878, 1.023)
rs7612445314 (56.577%)203 (36.577%)38 (6.847%)0.96(0.902, 1.104)1.05(0.955, 1.148)
rs1458038438 (78.919%)103 (18.559%)14 (2.523%)1.02(0.959, 1.078)1.10(0.988, 1.233)
rs133902322 (58.018%)192 (34.595%)41 (7.387%)0.97(0.927, 1.047)0.94(0.865, 1.017)