Stroke Research and Treatment

Genetics of Stroke


Publishing date
01 Oct 2011
Status
Published
Submission deadline
01 Apr 2011

Lead Editor

1Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via F.Sforza 35, 20122 Milan, Italy

2Department of Neurology, The Framingham Heart Study, Boston University School of Medicine, 72 East Concord Street, B601, Boston, MA 02118, USA

3Department of Neurological and Psychiatric Sciences, University of Florence, Viale Morgagni, 8550134 Firenze, Italy

4Hirnschlagbehandlungskette Universitätsspital Basel - Felix Platter Spital Petersgraben 4, 4031 Basel, Switzerland

5Department of Neurology, Environmental Health, Center for Environmental Genetics, University of Cincinnati, OH 45221, USA


Genetics of Stroke

Description

Stroke represents a leading cause of mortality and long-term disability. To relieve the heavy burden of stroke, we need to understand its pathogenic mechanisms to promote prevention and treatment. The genetic contribution to stroke is well established, and there is evidence that genetic factors influence stroke occurrence and outcome. Single gene disorders explain only a minority of stroke cases. However, for these diseases, identifying the underlying mutation allows diagnosis, prognostic information, and specific treatments in some cases and enables counselling of other family members.

Most strokes are usually assumed to be polygenic. The role of a number of genes has been extensively investigated in association with stroke, with controversial results.

The main focus of this special issue will be on the existing ongoing research on stroke genetics. The special issue will become an international forum for researchers to summarize the most recent developments and results in the field, with a special emphasis given to the results obtained within the last five years. The topics to be covered include, but are not limited to:

  • Update on monogenic disorders associated with stroke (new mutations, genotype-phenotype correlations, MRI development)
  • Recent developments in polygenic stroke including
    • New insight in association studies
    • Update in GWA results
    • Specific stroke subtype analysis such as results of cervical artery dissection genetic research
  • Standards and protocols to optimize stroke genetics research
  • Existing stroke genetics networks
  • Future research strategies

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/srt/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 212485
  • - Research Article

Gene-Drug Interaction in Stroke

Serena Amici | Maurizio Paciaroni | ... | Valeria Caso
  • Special Issue
  • - Volume 2011
  • - Article ID 179061
  • - Research Article

Genetics of Common Polygenic Ischaemic Stroke: Current Understanding and Future Challenges

Steve Bevan | Hugh S. Markus
  • Special Issue
  • - Volume 2011
  • - Article ID 208694
  • - Review Article

Genetics of Atrial Fibrillation and Possible Implications for Ischemic Stroke

Robin Lemmens | Sylvia Hermans | ... | Vincent Thijs
  • Special Issue
  • - Volume 2011
  • - Article ID 424759
  • - Research Article

Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality

Stella Trompet | Douwe Pons | ... | J. Wouter Jukema
  • Special Issue
  • - Volume 2011
  • - Article ID 534257
  • - Research Article

Lentiviral-Mediated shRNA Silencing of PDE4D Gene Inhibits Platelet-Derived Growth Factor-Induced Proliferation and Migration of Rat Aortic Smooth Muscle Cells

Lin Liu | Xiaowei Xu | ... | Wenli Sheng
  • Special Issue
  • - Volume 2011
  • - Article ID 920584
  • - Research Article

Association of TNF-857C>T, TNFRSF1A36A>G, and TNFRSF1B676T>G Polymorphisms with Ischemic Stroke in a Greek Population

Sofia Markoula | Anthoula Chatzikyriakidou | ... | Athanassios P. Kyritsis
  • Special Issue
  • - Volume 2011
  • - Article ID 792923
  • - Research Article

Functional Inflammatory Genotypes in Ischemic Stroke: Could We Use Them to Predict Age of Onset and Long-Term Outcome?

Stella Marousi | Anna Antonacopoulou | ... | John Ellul
Stroke Research and Treatment
 Journal metrics
Acceptance rate21%
Submission to final decision60 days
Acceptance to publication35 days
CiteScore2.430
Impact Factor-
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