Evaluation of ⁹⁹Mo and ^99𝑚Tc Productions Based on a High-Performance Cyclotron

Table 4

The 99𝑚Tc production yields estimated at EOB for different irradiation times at 15 and 20 MeV proton beams on 99.05% 100Mo-enriched metallic molybdenum and optimized target configuration. 500 𝜇A proton current and 500 W/cm² mean areal power density are considered on target. A series of production quality parameters are calculated and listed (see body text).

99𝑚Tc production	𝐸𝑃 = 15 MeV
Beam power on target (kW)	7.5
Beam power deposited inside Mo sample (kW)	1.41
Irradiation time	1 h	2 h	3 h	6 h
Integral yield (mCi/𝜇A)	5.32	10.05	14.28	24.38
In-target activity (Ci)	2.66	5.03	7.14	12.2
Specific activity (Ci/g)	1.16⋅10^6	1.10⋅10^6	1.04⋅10^6	8.86⋅10^5
Tc/Total activity	0.9877	0.9853	0.9848	0.9861
99𝑚Tc/Total activity	0.1809	0.2929	0.3693	0.4984
99𝑚Tc/99𝑚+𝑔Tc	0.2224	0.2103	0.1990	0.1699
Isotopic purity (IP)	0.2200	0.2081	0.1970	0.1682
Radionuclidic purity (RNP)	0.1831	0.2973	0.3750	0.5055
99𝑚Tc production	𝐸𝑃 = 20 MeV
Beam power on target (kW)	10.0
Beam power deposited inside Mo sample (kW)	3.95
Irradiation time	1 h	2 h	3 h	6 h
Integral yield (mCi/𝜇A)	10.35	19.58	27.81	47.56
In-target activity (Ci)	5.17	9.79	13.90	23.78
Specific Activity (Ci/g)	8.96⋅10^5	8.47⋅10^5	8.01⋅10^5	6.84⋅10^5
Tc/Total activity	0.9573	0.9488	0.9468	0.9491
99𝑚Tc/Total activity	0.2006	0.3162	0.3926	0.5190
99𝑚Tc/99𝑚+𝑔Tc	0.1862	0.1760	0.1665	0.1420
Isotopic purity (IP)	0.1698	0.1606	0.1520	0.1297
Radionuclidic purity (RNP)	0.2095	0.3333	0.4147	0.5468