Research Article
Tracing the Origin of Genotype II African Swine Fever Virus in China by Genomic Epidemiology Analysis
Table 3
List of function of the proteins harboring these anchor mutations.
| Genes | Functions | References |
| MGF 110-1L | Nonessential for in vitro propagation and nonaffect viral virulence | [56] | MGF 110-7L | Induces host cell translation suppression and stress granule formation by activating the PERK/PKR-eIF2 alpha pathway | [57] | MGF 360-10L | Implicated in the modulation of the type I interferon (IFN) response and associated to the virulence of the virus | [58] | MGF 505-5R | NA | NA | MGF 505-9R | NA | NA | K145R | A highly abundant viral protein accumulated diffusely in the cytoplasm of infected cells but nonessential for in vitro propagation of ASFV | [59] | NP419L | DNA ligase | [60] | I267L | An important virulence factor by inhibiting RNA polymerase III-RIG-I-mediated innate immunity | [61] |
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