Tracing the Origin of Genotype II African Swine Fever Virus in China by Genomic Epidemiology Analysis

Table 3

List of function of the proteins harboring these anchor mutations.

Genes	Functions	References
MGF 110-1L	Nonessential for in vitro propagation and nonaffect viral virulence	[56]
MGF 110-7L	Induces host cell translation suppression and stress granule formation by activating the PERK/PKR-eIF2 alpha pathway	[57]
MGF 360-10L	Implicated in the modulation of the type I interferon (IFN) response and associated to the virulence of the virus	[58]
MGF 505-5R	NA	NA
MGF 505-9R	NA	NA
K145R	A highly abundant viral protein accumulated diffusely in the cytoplasm of infected cells but nonessential for in vitro propagation of ASFV	[59]
NP419L	DNA ligase	[60]
I267L	An important virulence factor by inhibiting RNA polymerase III-RIG-I-mediated innate immunity	[61]