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Infected PRRSV strain | Subtype | Country | The days of inoculation (dpi) | Inoculated dose | Parameters of evaluation | Challenge group | Reference |
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ZD-1 | Subtype 1 | China | 21 | 4 × 104 TCID50 | Clinical symptoms | Medium clinical symptoms | This study |
Days of fever | 6 days (≥40.0°C) |
Pathological and histopathological lesions | Obvious pathological changes |
Viremia | Peaked at 7 dpi, longer than 21 days |
|
HLJB1 | Subtype 1 | China | 14 | 1 × 105 TCID50 | Clinical symptoms | Severe clinical symptoms, 3/7 pigs died | [16] |
Days of fever | 3 days (≥40°C) |
Pathological and histopathological lesions | Obvious pathological changes |
Viremia | Peaked at 7 dpi, longer than 21 days |
|
GZ11-G1 | Subtype 1 | China | 21 | 2 × 105 TCID50 | Clinical symptoms | Mild clinical symptoms | [17] |
Days of fever | 3 days (≥40.0°C) |
Pathological and histopathological lesions | Mild pathological changes |
Viremia | Peaked at 7 dpi, longer than 21 days |
|
PR40/2014 | Subtype 1 | Italy | 35 | 1 × 105 TCID50 | Clinical symptoms | Severe clinical symptoms, 3/7 pigs died | [49] |
Days of fever | 19 days (≥40°C) |
Pathological and histopathological lesions | Severe pathological changes |
Viremia | Peaked at 7 dpi, longer than 35 days |
|
WestSib13 | Subtype 2 | Russia | 14 | 5 × 104.7 TCID50 | Clinical symptoms | Severe clinical symptoms, 5/5 pigs died | [52] |
Days of fever | No fever |
Pathological and histopathological lesions | Severe pathological changes |
Viremia | Peaked at 6 dpi, all pigs died seven days after infection |
|
Lena | Subtype 3 | Belarusian | 21 | 1 × 106 TCID50 | Clinical symptoms | Severe clinical symptoms, 4/10 pigs died | [45] |
Days of fever | 25 days (≥40°C) |
Pathological and histopathological lesions | Severe pathological changes |
Viremia | Peaked at 14 dpi, longer than 35 days |
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