Transboundary and Emerging Diseases

Research Article

Galleria mellonella Invertebrate Model Mirrors the Pathogenic Potential of Mycoplasma alligatoris within the Natural Host

Table 2

Isolation of M. alligatoris from tissues of alligators infected intratracheally.
InfectiousBlood†Brain†Joints†
DoseDay 14 PIDay 28 PIDay 14 PIDay 28 PIDay 14 PIDay 28 PI
Control0/30/40/30/40/30/4
1010/40/50/40/50/40/5
1020/30/50/30/50/30/5
1031/30/61/30/60/30/6
1040/42/50/41/50/41/5‡
1053/41/50/40/50/40/5
1061/35/50/31/50/33/5§
1072/43/50/40/50/40/5
†Necropsies were performed on infected alligators at D14 PI (n = 4) or D28 PI (n = 5); control alligators (n = 7) were necropsied at D14 PI (n = 3) or D28 PI (n = 4). Note that the total number of alligators used for each infection dose was 9; however, two infected animals (102, n = 1; 106, n = 1) were euthanized prior to Day 14 and therefore are not included in the table. The number of alligators with positive cultures for each site at Day 14 or Day 28 PI/total number of necropsied at that time point is provided. ‡M. alligatoris was recovered from three of its four joints cultured. §M. alligatoris was recovered from all four joints of one alligator and from only one joint of two alligators.