Table of Contents Author Guidelines Submit a Manuscript
TheScientificWorldJOURNAL
Volume 1, Pages 168-180
http://dx.doi.org/10.1100/tsw.2001.23
Research Article

Amylin: Localization, Effects on Cerebral Arteries and on Local Cerebral Blood Flow in the Cat

Department of Internal Medicine, University Hospital, Lund, Sweden

Copyright © 2001 Lars Edvinsson et al.

Citations to this Article [29 citations]

The following is the list of published articles that have cited the current article.

  • Sérgio Gulbenkian, Rolf Uddman, and Lars Edvinsson, “Neuronal messengers in the human cerebral circulation,” Peptides, vol. 22, no. 6, pp. 995–1007, 2001. View at Publisher · View at Google Scholar
  • L. Edvinsson, “Calcitonin gene-related peptide (CGRP) and the pathophysiology of headache: Therapeutic implications,” CNS Drugs, vol. 15, no. 10, pp. 745–753, 2001. View at Publisher · View at Google Scholar
  • Kevin R. Oliver, Anna Wainwright, Lars Edvinsson, John D. Pickard, and Raymond G. Hill, “Immunohistochemical Localization of Calcitonin Receptor-Like Receptor and Receptor Activity-Modifying Proteins in the Human Cerebral Vasculature,” Journal of Cerebral Blood Flow & Metabolism, pp. 620–629, 2002. View at Publisher · View at Google Scholar
  • Lars Edvinsson, “New therapeutic target in primary headaches – blocking the CGRP receptor,” Expert Opinion on Therapeutic Targets, vol. 7, no. 3, pp. 377–383, 2003. View at Publisher · View at Google Scholar
  • Lars Edvinsson, “New therapeutic target in primary headaches - Blocking the CGRP receptor,” Expert Opinion on Therapeutic Targets, vol. 7, no. 3, pp. 377–383, 2003. View at Publisher · View at Google Scholar
  • Inger Jansen-Olesen, Linda Jørgensen, Ulla Engel, and Lars Edvinsson, “In-depth characterization of CGRP receptors in human intracranial arteries,” European Journal of Pharmacology, vol. 481, no. 2-3, pp. 207–216, 2003. View at Publisher · View at Google Scholar
  • L Edvinsson, “Blockade of CGRP receptors in the intracranial vasculature: a new target in the treatment of headache,” Cephalalgia, vol. 24, no. 8, pp. 611–622, 2004. View at Publisher · View at Google Scholar
  • Jochen K. Lennerz, Victor Rühle, Eugene P. Ceppa, Winfried L. Neuhuber, Nigel W. Bunnett, Eileen F. Grady, and Karl Messlinger, “Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: Differences between peripheral and central CGRP receptor distribution,” Journal of Comparative Neurology, vol. 507, no. 3, pp. 1277–1299, 2008. View at Publisher · View at Google Scholar
  • Lars Edvinsson, and Mattias Linde, “CGRP antagonists for the treatment of migraine: rationale and clinical data,” Clinical Investigation, vol. 2, no. 1, pp. 73–88, 2012. View at Publisher · View at Google Scholar
  • C S Walker, and D L Hay, “CGRP in the trigeminovascular system: a role for CGRP, adrenomedullin and amylin receptors?,” British Journal of Pharmacology, 2013. View at Publisher · View at Google Scholar
  • Sarah Srodulski, Savita Sharma, Adam B. Bachstetter, Jennifer M. Brelsfoard, Conrado Pascual, Xinmin Simon Xie, Kathryn E. Saatman, Linda J. Van Eldik, and Florin Despa, “Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin,” Molecular Neurodegeneration, vol. 9, 2014. View at Publisher · View at Google Scholar
  • Wei Qiao Qiu, and Haihao Zhu, “Amylin and its analogs: a friend or foe for the treatment of Alzheimer's disease?,” Frontiers in Aging Neuroscience, vol. 6, 2014. View at Publisher · View at Google Scholar
  • H Zhu, X Wang, M Wallack, H Li, I Carreras, A Dedeoglu, J-Y Hur, H Zheng, H Li, R Fine, M Mwamburi, X Sun, N Kowall, R A Stern, and W Q Qiu, “Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer’s disease,” Molecular Psychiatry, 2014. View at Publisher · View at Google Scholar
  • Wei Qiao Qiu, Max Wallack, Michael Dean, Elizabeth Liebson, Mkaya Mwamburi, and Haihao Zhu, “Association between Amylin and Amyloid-beta Peptides in Plasma in the Context of Apolipoprotein E4 Allele,” Plos One, vol. 9, no. 2, 2014. View at Publisher · View at Google Scholar
  • Wei Qiao Qiu, Rhoda Au, Haihao Zhu, Max Wallack, Elizabeth Liebson, Huajie Li, James Rosenzweig, Mkaya Mwamburi, and Robert A. Stern, “Positive Association between Plasma Amylin and Cognition in a Homebound Elderly Population,” Journal of Alzheimers Disease, vol. 42, no. 2, pp. 555–563, 2014. View at Publisher · View at Google Scholar
  • Thomas A. Lutz, and Urs Meyer, “Amylin at the interface between metabolic and neurodegenerative disorders,” Frontiers in Neuroscience, vol. 9, 2015. View at Publisher · View at Google Scholar
  • Christopher S. Walker, Sajedeh Eftekhari, Rebekah L. Bower, Andrea Wilderman, Paul A. Insel, Lars Edvinsson, Henry J. Waldvogel, Muhammad A. Jamaluddin, Andrew F. Russo, and Debbie L. Hay, “ A second trigeminal CGRP receptor: function and expression of the AMY 1 receptor ,” Annals of Clinical and Translational Neurology, 2015. View at Publisher · View at Google Scholar
  • Han Ly, and Florin Despa, “Hyperamylinemia as a risk factor for accelerated cognitive decline in diabetes,” Expert Review of Proteomics, pp. 1–3, 2015. View at Publisher · View at Google Scholar
  • Rania Soudy, Aarti Patel, Wen Fu, Kamaljit Kaur, David MacTavish, David Westaway, Rachel Davey, Jeffrey Zajac, and Jack Jhamandas, “Cyclic AC253, a novel amylin receptor antagonist, improves cognitive deficits in a mouse model of Alzheimer's,” Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2016. View at Publisher · View at Google Scholar
  • Erming Wang, Haihao Zhu, Xiaofan Wang, Adam Gower, Max Wallack, Jan Krzysztof Blusztajn, Neil Kowall, and Wei Qiao Qiu, “Amylin Treatment Reduces Neuroinflammation and Ameliorates Abnormal Patterns of Gene Expression in the Cerebral Cortex of an Alzheimer’s Disease Mouse Model,” Journal of Alzheimer's Disease, pp. 1–15, 2016. View at Publisher · View at Google Scholar
  • Debbie L. Hay, “Amylin,” Headache: The Journal of Head and Face Pain, vol. 57, pp. 89–96, 2017. View at Publisher · View at Google Scholar
  • Ana Marta de Matos, Maria Paula de Macedo, and Amélia Pilar Rauter, “Bridging Type 2 Diabetes and Alzheimer's Disease: Assembling the Puzzle Pieces in the Quest for the Molecules With Therapeutic and Preventive Potential,” Medicinal Research Reviews, 2017. View at Publisher · View at Google Scholar
  • Haihao Zhu, Xiehua Xue, Erming Wang, Max Wallack, Hana Na, Jacob M. Hooker, Neil Kowall, Qiushan Tao, Thor D. Stein, Benjamin Wolozin, and Wei Qiao Qiu, “Amylin receptor ligands reduce the pathological cascade of Alzheimer's disease,” Neuropharmacology, 2017. View at Publisher · View at Google Scholar
  • Yun Zhang, and Weihong Song, “Islet Amyloid Polypeptide: Another Key Molecule in Alzheimer’s Pathogenesis?,” Progress in Neurobiology, 2017. View at Publisher · View at Google Scholar
  • Loqman A. Mohamed, Haihao Zhu, Youssef M. Mousa, Erming Wang, Wei Qiao Qiu, and Amal Kaddoumi, “Amylin Enhances Amyloid-β Peptide Brain to Blood Efflux Across the Blood-Brain Barrier,” Journal of Alzheimer's Disease, pp. 1–13, 2017. View at Publisher · View at Google Scholar
  • Haihao Zhu, Robert A. Stern, Qiushan Tao, Alexandra Bourlas, Maritza D. Essis, Meenakshi Chivukula, James Rosenzweig, Devin Steenkamp, Weiming Xia, Gustavo A. Mercier, Yorghos Tripodis, Martin Farlow, Neil Kowall, and Wei Q. Qiu, “An amylin analog used as a challenge test for Alzheimer's disease,” Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2017. View at Publisher · View at Google Scholar
  • Weigang Cai, Chan-Hee Kim, Hye-Jin Go, Michaela Egertová, Cleidiane G. Zampronio, Alexandra M. Jones, Nam Gyu Park, and Maurice R. Elphick, “Biochemical, Anatomical, and Pharmacological Characterization of Calcitonin-Type Neuropeptides in Starfish: Discovery of an Ancient Role as Muscle Relaxants,” Frontiers in Neuroscience, vol. 12, 2018. View at Publisher · View at Google Scholar
  • Lars Edvinsson, “The CGRP Pathway in Migraine as a Viable Target for Therapies,” Headache: The Journal of Head and Face Pain, vol. 58, pp. 33–47, 2018. View at Publisher · View at Google Scholar
  • Qiushan Tao, Haihao Zhu, Xi Chen, Robert A. Stern, Neil Kowall, Rhoda Au, Jan Krzysztof Blusztajn, and Wei Qiao Qiu, “Pramlintide: The Effects of a Single Drug Injection on Blood Phosphatidylcholine Profile for Alzheimer’s Disease,” Journal of Alzheimer's Disease, vol. 62, no. 2, pp. 597–609, 2018. View at Publisher · View at Google Scholar