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Volume 2, Pages 1491-1500
http://dx.doi.org/10.1100/tsw.2002.352
Mini-Review Article

Enhanced Hepatocarcinogenicity Due to Agonists of Peroxisome Proliferator-Activated Receptors in Senescent Rats: Role of Peroxisome Proliferation, Cell Proliferation, and Apoptosis

University of Missouri-Kansas City, 2411 Holmes Street, M3-115, Kansas City, MO 64108-2792, USA

Received 18 April 2002; Revised 22 April 2002; Accepted 24 April 2002

Copyright © 2002 Jihan Youssef and Mostafa Badr.

Citations to this Article [13 citations]

The following is the list of published articles that have cited the current article.

  • C Chao, J Youssef, M Badr, M Rezaiekhaleigh, and Ls Birnbaum, “Senescence-associated decline in hepatic peroxisomal enzyme activities corresponds with diminished levels of retinoid X receptor alpha, but not peroxisome proliferator-activated receptor alpha,” Mechanisms Of Ageing And Development, vol. 123, no. 11, pp. 1469–1476, 2002. View at Publisher · View at Google Scholar
  • Eric Boitier, Jean-Charles Gautier, and Ruth Roberts, “Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: Relevance for human health and disease,” Comparative Hepatology, vol. 2, 2003. View at Publisher · View at Google Scholar
  • Jihan Youssef, and Mostafa Badr, “Role of peroxisome proliferator-activated receptors in inflammation control,” Journal of Biomedicine and Biotechnology, vol. 2004, no. 3, pp. 156–166, 2004. View at Publisher · View at Google Scholar
  • Mostafa Z. Badr, and Linda S. Birnbaum, “Enhanced potential for oxidative stress in livers of senescent rats by the peroxisome proliferator-activated receptor alpha agonist perfluorooctanoic acid,” Mechanisms of Ageing and Development, vol. 125, no. 1, pp. 69–75, 2004. View at Publisher · View at Google Scholar
  • Kar Neng Lai, Loretta Y.Y. Chan, and Joseph C.K. Leung, “Mechanisms of tubulointerstitial injury in IgA nephropathy,” Kidney International, vol. 67, no. s94, pp. s110–s115, 2005. View at Publisher · View at Google Scholar
  • Jihan A. Youssef, and Mostafa Z. Badr, “Aging and enhanced hepatocarcinogenicity by peroxisome proliferator-activated receptor alpha agonists,” Ageing Research Reviews, vol. 4, no. 1, pp. 103–118, 2005. View at Publisher · View at Google Scholar
  • Nagalakshmi Keshava, and Jane C. Caldwell, “Key issues in the role of peroxisorne proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity,” Environmental Health Perspectives, vol. 114, no. 9, pp. 1464–1470, 2006. View at Publisher · View at Google Scholar
  • Nagalakshmi Keshava, and Jane C. Caldwell, “Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity,” Environmental Health Perspectives, vol. 114, no. 9, pp. 1464–1470, 2006. View at Publisher · View at Google Scholar
  • Kai Uwe Chow, Daniel Nowak, Bernd Schneider, Simone Boehrer, Dieter Hoelzer, Eckhart Weidmann, Soo-Zin Kim, Martina Komor, Paris S. Mitrou, and Wolf-Karsten Hofmann, “In vivo drug-response in patients with leukemic non-Hodgkin's lymphomas is associated with in vitro chemosensitivity and gene expression profiling,” Pharmacological Research, vol. 53, no. 1, pp. 49–61, 2006. View at Publisher · View at Google Scholar
  • Marion Peyrou, Pierluigi Ramadori, Lucie Bourgoin, and Michelangelo Foti, “PPARs in Liver Diseases and Cancer: Epigenetic Regulation by MicroRNAs,” PPAR Research, vol. 2012, pp. 1–16, 2012. View at Publisher · View at Google Scholar
  • Tiziana Sinagra, Alessandra Tamburella, Vincenzo Urso, Ilias Siarkos, Filippo Drago, Claudio Bucolo, and Salvatore Salomone, “Reversible inhibition of vasoconstriction by thiazolidinediones related to PI3K/Akt inhibition in vascular smooth muscle cells,” Biochemical Pharmacology, vol. 85, no. 4, pp. 551–559, 2013. View at Publisher · View at Google Scholar
  • Elisa Paolicchi, Paola Pacetti, Elisa Giovannetti, Andrea Mambrini, Massimo Orlandi, Francesco Crea, Antonello A. Romani, Roberta Tartarini, Romano Danesi, Godefridus J. Peters, and Maurizio Cantore, “A single nucleotide polymorphism in EZH2 predicts overall survival rate in patients with cholangiocarcinoma,” Oncology Letters, vol. 6, no. 5, pp. 1487–1491, 2013. View at Publisher · View at Google Scholar
  • Yuval Ramot, Arianna Mastrofrancesco, Emanuela Camera, Pierre Desreumaux, Ralf Paus, and Mauro Picardo, “ The role of PPAR γ -mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology ,” Experimental Dermatology, vol. 24, no. 4, pp. 245–251, 2015. View at Publisher · View at Google Scholar