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TheScientificWorldJOURNAL
Volume 7, Pages 233-241
http://dx.doi.org/10.1100/tsw.2007.63
Review Article

Galactosaminoglycan Function and Oligosaccharide Structure Determination

1Department of Physiological Chemistry and Pathobiochemistry, UKM, University of Münster, D-48149, Münster, Germany
2Institute for Medical Physics and Biophysics, Biomedical Analysis Department, UKM, University of Münster, D-48149, Münster, Germany
3Department of Chemistry and Biology, University of Arad, RO-310139, Arad, Romania
4Mass Spectrometry Division, National Institute for Research and Development in Electrochemistry and Condensed Matter, RO-300224, Timisoara, Romania

Received 2 December 2006; Revised 29 January 2007; Accepted 2 February 2007

Academic Editor: Martin Goette

Copyright © 2007 Daniela G. Seidler et al.

Abstract

This review will discuss the importance of sequencing long chondroitin sulfate and dermatan sulfate chains specifically derived from decorin. Decorin is a member of the small leucine-rich repeat proteoglycans and ubiquitously expressed primarily in the skin. Sequence information and diverse function of glycosaminoglycans is further influenced by variable expression through the core protein indicating the importance to analyse glycosaminoglycans from specific proteoglycans.