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TheScientificWorldJOURNAL
Volume 7, Pages 808-817
http://dx.doi.org/10.1100/tsw.2007.150
Review Article

Botulinum Toxin Use in the Lower Urinary Tract

Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

Received 29 October 2006; Revised 5 February 2007; Accepted 9 February 2007

Academic Editor: Christopher F. Chapple

Copyright © 2007 Shelby N. Morrisroe and Michael B. Chancellor.

Abstract

Botulinum toxins are well known for their ability to disrupt neurotransmission and cause muscle paralysis. Recently, urologists have discovered their beneficial effects in patients with neurogenic and overactive bladder conditions. This review is intended to provide a quick overview for urologists of the structure, function, and clinical uses of botulinum neurotoxin A in the lower urinary tract.