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TheScientificWorldJOURNAL
Volume 7, Pages 155-166
http://dx.doi.org/10.1100/tsw.2007.201
Mini-Review Article

MicroRNA Profiling: From Dark Matter to White Matter, or Identifying New Players in Neurobiology

Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA

Received 28 June 2007; Accepted 9 July 2007

Academic Editors: D. Shurtleff and S. Ferre

Copyright © 2007 Anna M. Krichevsky.

Citations to this Article [44 citations]

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  • John Ravits, and Bryan J. Traynor, “Current and Future Directions in Genomics of Amyotrophic Lateral Sclerosis,” Physical Medicine and Rehabilitation Clinics of North America, vol. 19, no. 3, pp. 461–477, 2008. View at Publisher · View at Google Scholar
  • Andreas Walter Kuss, and Wei Chen, “MicroRNAs in brain function and disease,” Current Neurology and Neuroscience Reports, vol. 8, no. 3, pp. 190–197, 2008. View at Publisher · View at Google Scholar
  • Wang-Xia Wang, Bernard R. Wilfred, Donald A. Baldwin, R. Benjamin Isett, Na Ren, Arnold Stromberg, and Peter T. Nelson, “Focus on RNA isolation: Obtaining RNA for microRNA (miRNA) expression profiling analyses of neural tissue,” Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, vol. 1779, no. 11, pp. 749–757, 2008. View at Publisher · View at Google Scholar
  • Peter T. Nelson, Wang-Xia Wang, Bernard R. Wilfred, and Guiliang Tang, “Technical variables in high-throughput miRNA expression profiling: Much work remains to be done,” Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, vol. 1779, no. 11, pp. 758–765, 2008. View at Publisher · View at Google Scholar
  • Nai-Kui Liu, Xiao-Fei Wang, Qing-Bo Lu, and Xiao-Ming Xu, “Altered microRNA expression following traumatic spinal cord injury,” Experimental Neurology, vol. 219, no. 2, pp. 424–429, 2009. View at Publisher · View at Google Scholar
  • William Kong, Jian-Jun Zhao, Lili, and Jin Q. Cheng, “Strategies for profiling MicroRNA expression,” Journal of Cellular Physiology, vol. 218, no. 1, pp. 22–25, 2009. View at Publisher · View at Google Scholar
  • Shu-Ting Wang, Cai Li, and Lei Liu, “miRNA microarray technology in miRNA profiling,” Current Bioinformatics, vol. 4, no. 2, pp. 141–148, 2009. View at Publisher · View at Google Scholar
  • Manish Bhomia, Nagaraja Balakathiresan, Anuj Sharma, Paridhi Gupta, Roopa Biswas, and Radha Maheshwari, “Analysis of microRNAs induced by Venezuelan equine encephalitis virus infection in mouse brain,” Biochemical and Biophysical Research Communications, vol. 395, no. 1, pp. 11–16, 2010. View at Publisher · View at Google Scholar
  • Lars Dyrskjøt, Karina Dalsgaard-Sørensen, Marie Stampe-Ostenfeld, Karin Birkenkamp-Demtroder, Kasper Thorsen, Claus L. Andersen, Mogens Kruhøffer, Jens L. Jensen, and Torben F. Ørntoft, “DNA Microarrays and Genetic Testing,” Molecular Diagnostics, pp. 247–265, 2010. View at Publisher · View at Google Scholar
  • Nai-Kui Liu, and Xiao-Ming Xu, “MicroRNA in central nervous system trauma and degenerative disorders,” Physiological Genomics, vol. 43, no. 10, pp. 571–580, 2011. View at Publisher · View at Google Scholar
  • Mateo Ziu, Lauren Fletcher, Shushan Rana, David F. Jimenez, and Murat Digicaylioglu, “Temporal differences in microRNA expression patterns in astrocytes and neurons after ischemic injury,” PLoS ONE, vol. 6, no. 2, 2011. View at Publisher · View at Google Scholar
  • Kemal Ugur Tufekci, Meryem Gulfem Oner, Sermin Genc, and Kursad Genc, “MicroRNAs and Multiple Sclerosis,” Autoimmune Diseases, vol. 2011, pp. 1–27, 2011. View at Publisher · View at Google Scholar
  • Nai-Kui Liu, “Neuroprotection and its molecular mechanism following spinal cord injury,” Neural Regeneration Research, vol. 7, no. 26, pp. 2051–2062, 2012. View at Publisher · View at Google Scholar
  • Kai C. Sonntag, Tsung-Ung W. Woo, and Anna M. Krichevsky, “Converging miRNA functions in diverse brain disorders: A case for miR-124 and miR-126,” Experimental Neurology, vol. 235, no. 2, pp. 427–435, 2012. View at Publisher · View at Google Scholar
  • Min Ki Jee, Jin Sun Jung, Young Bin Im, Sung Jun Jung, and Soo Kyung Kang, “Silencing of miR20a Is Crucial for Ngn1-Mediated Neuroprotection in Injured Spinal Cord,” Human Gene Therapy, vol. 23, no. 5, pp. 508–520, 2012. View at Publisher · View at Google Scholar
  • Fanglei Zhuang, Ryan T. Fuchs, and G. Brett Robb, “Small RNA Expression Profiling by High-Throughput Sequencing: Implications of Enzymatic Manipulation,” Journal of Nucleic Acids, vol. 2012, pp. 1–15, 2012. View at Publisher · View at Google Scholar
  • Jack G. Walleshauser III, Trace Kessler, Danielle Morse, Bakhos A. Tannous, and Norman H. L. Chiu, “A Simple Approach for Evaluating Total MicroRNA Extraction from Mouse Brain Tissues,” Journal of Analytical Sciences, Methods and Instrumentation, vol. 02, no. 01, pp. 5–12, 2012. View at Publisher · View at Google Scholar
  • Jessie S. Truettner, Dario Motti, and W. Dalton Dietrich, “MicroRNA overexpression increases cortical neuronal vulnerability to injury,” Brain Research, 2013. View at Publisher · View at Google Scholar
  • Li Zhang, and Hong Jiang, “MicroRNAs and polyglutamine diseases,” Chinese Journal of Medical Genetics, vol. 30, no. 6, pp. 683–686, 2013. View at Publisher · View at Google Scholar
  • Mateo Ziu, Lauren Fletcher, Jennifer G. Savage, David F. Jimenez, Murat Digicaylioglu, and Viktor Bartanusz, “Spatial and temporal expression levels of specific microRNAs in a spinal cord injury mouse model and their relationship to the duration of compression,” The Spine Journal, 2013. View at Publisher · View at Google Scholar
  • Sayak Ganguli, Sasti Gopal Das, Hirak Jyoti Chakraborty, Sohini Gupta, and Abhijit Datta, “Identification of regulatory sequence signatures in microRNA precursors implicated in neurological disorders,” Advances in Bioscience and Biotechnology, vol. 04, no. 05, pp. 26–33, 2013. View at Publisher · View at Google Scholar
  • Jun Dong, Meng Lu, Xijing He, Junkui Xu, Jie Qin, Zhijian Cheng, Baobao Liang, Dong Wang, and Haopeng Li, “Identifying the role of microRNAs in spinal cord injury,” Neurological Sciences, 2014. View at Publisher · View at Google Scholar
  • Ting-yi Sun, Xiao-rui Chen, Zi-long Liu, Li-li Zhao, Yong-xiang Jiang, Guo-qiang Qu, Rong-shuai Wang, Si-zhe Huang, and Liang Liu, “Expression profiling of MicroRNAs in hippocampus of rats following traumatic brain injury,” Journal of Huazhong University of Science and Technology [Medical Sciences], vol. 34, no. 4, pp. 548–553, 2014. View at Publisher · View at Google Scholar
  • Liang Liu, Tingyi Sun, Zilong Liu, Xiaorui Chen, Lili Zhao, Guoqiang Qu, and Qingjie Li, “Traumatic Brain Injury Dysregulates MicroRNAs to Modulate Cell Signaling in Rat Hippocampus,” Plos One, vol. 9, no. 8, 2014. View at Publisher · View at Google Scholar
  • Shun Min Xing, Jinxin Wang, Xiang He, Jin Lai, Lianbing Shen, Dechun Chen, Kai Fu, and Junming Tan, “Identification of disease-related miRNAs based on co-expression network in spinal cord injury,” International Journal of Neuroscience, pp. 140924103426003, 2014. View at Publisher · View at Google Scholar
  • Defeng Zou, Yi Chen, Yaxin Han, Chen Lv, and Guanjun Tu, “Overexpression of microRNA-124 promotes the neuronal differentiation of bone marrow-derived mesenchymal stem cells,” Neural Regeneration Research, vol. 9, no. 12, pp. 1241–1248, 2014. View at Publisher · View at Google Scholar
  • Manuel Nieto-Diaz, Francisco J. Esteban, David Reigada, Teresa Munoz-Galdeano, Monica Yunta, Marcos Caballero-Lopez, Rosa Navarro-Ruiz, Angela del Aguila, and Rodrigo M. Maza, “MicroRNA dysregulation in spinal cord injury: causes, consequences, and therapeutics,” Frontiers in Cellular Neuroscience, vol. 8, 2014. View at Publisher · View at Google Scholar
  • Bin Ning, Lu Gao, Rong-Han Liu, Yang Liu, Na-Sha Zhang, and Zhe-Yu Chen, “microRNAs in Spinal Cord Injury: Potential Roles and Therapeutic Implications,” International Journal of Biological Sciences, vol. 10, no. 9, pp. 997–1006, 2014. View at Publisher · View at Google Scholar
  • Jimena Quinzanos-Fresnedo, and Roberto Carlos Sahagun-Olmos, “Micro RNA and its role in the pathophysiology of spinal cord injury a further step towards neuroregenerative medicine,” Cirugia Y Cirujanos, vol. 83, no. 5, pp. 442–447, 2015. View at Publisher · View at Google Scholar
  • Jimena Quinzaños-Fresnedo, and Roberto Carlos Sahagún-Olmos, “Micro RNA and its role in the pathophysiology of spinal cord injury — A further step towards neuroregenerative medicine,” Cirugía y Cirujanos (English Edition), vol. 83, no. 5, pp. 442–447, 2015. View at Publisher · View at Google Scholar
  • Jimena Quinzaños-Fresnedo, and Roberto Carlos Sahagún-Olmos, “Micro ARN y su papel en la fisiopatología de la lesión medular; un paso más hacia la medicina neurorregenerativa,” Cirugía y Cirujanos, 2015. View at Publisher · View at Google Scholar
  • Hanna Hartmann, Kristin Hoehne, Elke Rist, Andrew Mark Louw, and Burkhard Schlosshauer, “miR-124 disinhibits neurite outgrowth in an inflammatory environment,” Cell and Tissue Research, 2015. View at Publisher · View at Google Scholar
  • Liudmila N. Novikova, Paul J. Kingham, Rebecca Wiberg, and Samuel Jonsson, “Investigation of the expression of myogenic transcription factors, microRNAs and muscle-specific E3 ubiquitin ligases in the medial gastrocnemius and soleus muscles following peripheral nerve injury,” PLoS ONE, vol. 10, no. 12, 2015. View at Publisher · View at Google Scholar
  • Yongxin Luan, Mo Chen, and Lixiang Zhou, “MiR-17 Targets PTEN and Facilitates Glial Scar Formation after Spinal Cord Injuries via the PI3K/Akt/mTOR Pathway,” Brain Research Bulletin, 2016. View at Publisher · View at Google Scholar
  • Jiang-Hu Huang, Cao Yong, Lei Zeng, Guan Wang, Min Cao, Hong-Bin Lu, and Jian-Zhong Hu, “Tetramethylpyrazine Enhances Functional Recovery after Contusion Spinal Cord Injury by Modulation of MicroRNA-21, FasL, PDCD4 and PTEN Expression,” Brain Research, 2016. View at Publisher · View at Google Scholar
  • Anne Baroin-Tourancheau, Xavier Benigni, Soraya Doubi-Kadmiri, Mohammed Taouis, and Laurence Amar, “Lessons from microRNA Sequencing Using Illumina Technology,” Advances in Bioscience and Biotechnology, vol. 07, no. 07, pp. 319–328, 2016. View at Publisher · View at Google Scholar
  • Yuqing Jiang, Yin Ding, Luming Nong, Gongming Gao, Shujie Zhao, Haibo Li, Dong Zhou, and Nanwei Xu, “MicroRNA-21 promotes neurite outgrowth by regulating PDCD4 in a rat model of spinal cord injury,” Molecular Medicine Reports, vol. 16, no. 3, pp. 2522–2528, 2017. View at Publisher · View at Google Scholar
  • Huaguang Zhu, Rong Xie, Xiaodong Liu, Jiajun Shou, Wentao Gu, Shixin Gu, and Xiaoming Che, “MicroRNA-494 improves functional recovery and inhibits apoptosis by modulating PTEN/AKT/mTOR pathway in rats after spinal cord injury,” Biomedicine & Pharmacotherapy, vol. 92, pp. 879–887, 2017. View at Publisher · View at Google Scholar
  • Yi Guo, and Shizhen Niu, “ MiR-25 protects PC-12 cells from H 2 O 2 mediated oxidative damage via WNT/β-catenin pathway ,” The Journal of Spinal Cord Medicine, pp. 1–10, 2017. View at Publisher · View at Google Scholar
  • Zhongju Shi, Hengxing Zhou, Lu Lu, Xueying Li, Zheng Fu, Jun Liu, Yi Kang, Zhijian Wei, Bin Pan, Lu Liu, Xiaohong Kong, and Shiqing Feng, “The roles of microRNAs in spinal cord injury,” International Journal of Neuroscience, pp. 1–12, 2017. View at Publisher · View at Google Scholar
  • Jing Liu, and Yaochi Wu, “Electro-acupuncture-modulated miR-214 prevents neuronal apoptosis by targeting Bax and inhibits sodium channel Nav1.3 expression in rats after spinal cord injury,” Biomedicine & Pharmacotherapy, vol. 89, pp. 1125–1135, 2017. View at Publisher · View at Google Scholar
  • Yoon Young Kim, Harry Min, Hoon Kim, Young Min Choi, Hung Ching Liu, and Seung-Yup Ku, “Differential MicroRNA Expression Profile of Human Embryonic Stem Cell-Derived Cardiac Lineage Cells,” Tissue Engineering and Regenerative Medicine, vol. 14, no. 2, pp. 163–169, 2017. View at Publisher · View at Google Scholar
  • Tao Chen, Zongwen Huang, Yingxian Zhu, Juyuan Bu, Guowei Li, and Xiaoyu Xiao, “MiR-103 alleviates autophagy and apoptosis by regulating SOX2 in LPS-injured PC12 cells and SCI rats,” Iranian Journal of Basic Medical Sciences, vol. 21, no. 3, pp. 292–300, 2018. View at Publisher · View at Google Scholar
  • Jin Yang, You-Cui Wang, Ling Jiang, Song-Jun Fu, Xue-Fei Han, Ting-Hua Wang, Liu-Lin Xiong, Xiang He, and Jia Liu, “Oligodendrocyte precursor cell transplantation promotes functional recovery following contusive spinal cord injury in rats and is associated with altered MicroRNA expression,” Molecular Medicine Reports, vol. 17, no. 1, pp. 771–782, 2018. View at Publisher · View at Google Scholar