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Volume 9 (2009), Pages 5-9
Case Study

Surgically Discovered Xanthogranulomatous Pyelonephritis Invading Inferior Vena Cava with Coexisting Renal Cell Carcinoma

1Department of Urology, University of Iowa, Iowa City, IA, USA
2Department of Pathology, University of Iowa, Iowa City, IA, USA

Received 19 November 2008; Revised 2 January 2009; Accepted 4 January 2009

Academic Editor: Peter E. Clark

Copyright © 2009 Henry M. Rosevear et al.


Xanthogranulomatous pyelonephritis (XGP) is a chronic inflammatory process that results in replacement of renal and/or perirenal tissue with a diffuse infiltrate of inflammatory cells referred to as xanthoma cells. We present a case of a 49-year-old man with an incidentally discovered renal mass with inferior vena cava (IVC) thrombus, who was found intraoperatively to have a significant inflammatory process involving the posterior wall of his IVC and right renal vein consistent with XGP surrounding a focus of clear cell renal cell carcinoma in the midportion of his right kidney.