The Scientific World Journal

The Scientific World Journal / 2009 / Article
Special Issue

Sexual Dysfunction

View this Special Issue

Review Article | Open Access

Volume 9 |Article ID 273087 | https://doi.org/10.1100/tsw.2009.79

Robert J. Feeley, Abdulmaged M. Traish, "Obesity and Erectile Dysfunction: Is Androgen Deficiency the Common Link?", The Scientific World Journal, vol. 9, Article ID 273087, 9 pages, 2009. https://doi.org/10.1100/tsw.2009.79

Obesity and Erectile Dysfunction: Is Androgen Deficiency the Common Link?

Academic Editor: Ricardo Munarriz
Received06 Apr 2009
Revised12 Jun 2009
Accepted22 Jun 2009

Abstract

Obesity is associated with increased risk of erectile dysfunction (ED); however, the underlying causes of ED in obese individuals remain poorly defined. The aim of this review is to discuss the evidence available on the relationship between obesity and ED. A search of published studies in PubMed from 1970 through 2009 was conducted, and relevant articles were evaluated and discussed.Visceral obesity is a public health threat, and is associated with increased risk of diabetes, vascular disease, endothelial dysfunction, and ED. Plasma testosterone levels are reduced in obesity, further contributing to an increased risk of vascular pathology in obesity. The recognition of the relationship between obesity, reduced testosterone levels, and ED has paved the way for new approaches to manage and treat obese, hypogonadal patients with ED. Obesity profoundly and adversely impacts overall health and, in particular, vascular health, by increasing proinflammatory factors, altering endothelial function and the androgen endocrine milieu, thus increasing the risk of ED.


More related articles

 PDF Download Citation Citation
 Order printed copiesOrder
Views291
Downloads984
Citations

Related articles

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.