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Volume 10, Pages 301-307
Case Study

Hepatocellular Carcinoma Masquerading as a Large Renal Mass with Hepatic Invasion

1Department of Urology, University of Iowa, Iowa City, IA, USA
2Department of Surgery, University of Iowa, Iowa City, IA, USA
3Department of Pathology, University of Iowa, Iowa City, IA, USA

Received 10 November 2009; Revised 30 January 2010; Accepted 5 February 2010

Academic Editor: Anthony Atala

Copyright © 2010 Joseph R. N. Zabell et al.


Large masses are evaluated with imaging to assess primary origin and tumor spread. We present the unusual case of a 53-year-old male with a 17-cm right upper quadrant mass suspected to be renal or adrenal in origin based on radiographic findings. After surgical excision, the mass was subsequently discovered to be primary hepatocellular carcinoma with direct extension to the kidney and adrenal gland. A diagnosis of chronic hepatitis B was made postoperatively. Primary hepatocellular carcinoma with direct renal extension is an exceedingly rare occurrence based on our experience and review of the published literature.