Review Article
Protein Disulfide Isomerase and Host-Pathogen Interaction
Table 1
Summary of the main PDI types and redox activity expressed in different groups of pathogens.
| Pathogen group | PDI (thioredoxin motif) | Redox activity | Reference |
| Leishmania major | 5 isoforms (CGHC, CRYC) | Oxidase-isomerase | [16, 23, 24] | amazonensis | 5 isoforms (CGHC, CRYC) | Reductase-isomerase | [16, 23, 24] | infantum | 5 isoforms (CGHC) | ND | [23] | braziliensis | 3 isoforms (CGHC) | ND | [23] |
| Trypanosoma cruzi | 5 isoforms (CXXC) | ND | [25, 26] |
| Plasmodium falciparum | 4 isoforms (2x CGHC) | Oxidase-reductase | [27, 28] |
| Toxoplasma gondii | ND | ND | [29] |
| Entamoeba histolytica | 1 isorform, 38 kDa (2x CGHC) | Oxidase-reductase | [30] |
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