Sequence homologies of MK and PTN. (a) Amino acid sequence of human MK and murine MK as well as human MK and human PTN. Human and murine MK show 87% amino acid sequence identity; human MK and PTN share 50% sequence homology. = residues identical in both sequences [38ā40]. (b) Web logos displaying sequence homology of human MK, murine MK, chicken MK, miple1, and human PTN in information bits [50]. A large overall height indicates strong conservation of the corresponding amino acid in that position; the height within the stack shows the relative frequency of the amino acid at that position. Cysteine residues (black circle) and basic amino acids (green circle) are highly conserved within different species of the MK family.
