Review Article

Embryonic Regulation of the Mouse Hematopoietic Niche

Figure 2

Hematopoietic environment in the YS. Mesodermal cells, the ancestors of hematopoietic cells, differentiate into both hematopoietic cells within blood islands and endothelial cells (ECs) outside of that region. Blood vessels, consisting of endothelial cells and containing primitive erythrocytes and macrophages, are located among cells originating from endodermal and mesodermal cells.
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