Pro- and Antiapoptotic Markers in Upper Tract Urothelial Carcinoma Associated with Balkan Endemic Nephropathy

Table 1

Association of antiapoptotic biomarkers expression with pathological characteristics of UTUC.

UUC	𝑁	Altered expression of biomarker
		Survivin	𝑃<	Bcl-2	𝑃<
Low grade			N.S.		N.S.
BEN	16	5		3
Control	25	12		4
High grade			0.05		N.S.
BEN	28	21		4
Control	36	17		5
Low stage			N.S.		N.S.
BEN	17	10		2
Control	19	8		4
High stage			N.S.		N.S.
BEN	27	16		5
Control	42	21		5
Papillary growth			N.S.		N.S.
BEN	12	4		2
Control	27	14		5
Solid growth			0.05		N.S.
BEN	32	22		5
Control	34	15		4
LV invasion: yes			N.S.		N.S.
BEN	10	8		1
Control	20	10		2
Necrosis: yes			N.S.		N.S.
BEN	19	12		4
Control	25	12		2
Nonmetaplastic			N.S.		N.S.
BEN	34	18		4
Control	48	22		5
Metaplastic			N.S.		N.S.
BEN	10	8		3
Control	13	7		3

χ ² test was performed.
N.S.: no significance.