Clinical Study
Pro- and Antiapoptotic Markers in Upper Tract Urothelial Carcinoma
Associated with Balkan Endemic Nephropathy
Table 4
Multivariate logistic regression and linear regression analysis of all UTUC.
| Logistic regresion Model | Dependent variable | Predictor | | S.E. | Wald | Sig. | Exp () | 95.0% C.I. | for EXP () | sig. | | | | | | | | Lower | Upper |
| 0.014 | Survivin | Fas | −0.996 | 0.412 | 5.841 | 0.016 | 0.369 | 0.165 | 0.828 | | | Constant | 0.659 | 0.318 | 4.296 | 0.038 | 1.933 | | |
| 0.0001 | Bcl-2 | Caspase 3 | 0.362 | 0.111 | 10.736 | 0.001 | 1.437 | 1.157 | 1.784 | | | Constant | −2.667 | 0.421 | 40.215 | 0.000 | 0.069 | | |
| 0.0001 | Bax | Group | 1.542 | 0.490 | 9.919 | 0.002 | 4.673 | 1.790 | 12.199 | | | Stage | 1.125 | 0.531 | 4.484 | 0.034 | 3.080 | 1.087 | 8.723 | | | Growth | −1.031 | 0.519 | 3.940 | 0.047 | 0.357 | 0.129 | 0.987 | | |
Caspase 3 | 0.326 | 0.148 | 4.841 | 0.028 | 1.385 | 1.036 | 1.851 | | | Constant | −0.945 | 0.445 | 4.500 | 0.034 | 0.389 | | |
| 0.0001 | Fas | Pelvis/Ureter | −1.312 | 0.531 | 6.102 | 0.013 | 0.269 | 0.095 | 0.763 | | | Metaplastic | −1.215 | 0.597 | 4.138 | 0.042 | 0.297 | 0.092 | 0.957 | | |
Caspase 3 | 0.318 | 0.134 | 5.622 | 0.018 | 1.374 | 1.057 | 1.787 | | | Constant | 1.793 | 0.722 | 6.160 | 0.013 | 6.008 | | |
| linear regresion model | Dependent variable | Predictor | | S.E. | Standardized coefficient beta | | Sig. |
| F 12.542 |
Caspase 3 | Differentiation | −2.970 | 1.324 | | −0.196 | | −2.243 | 0.027 | sig. 0.0001 | | Bcl-2 | 9.967 | 1.759 | | .0486 | | 5.665 | 0.000 | | | Constant | −8.376 | 3.075 | | | | −2.724 | 0.008 |
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