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Volume 11, Pages 2310-2329
http://dx.doi.org/10.1100/2011/865239
Review Article

Tracheobronchial Manifestations of Aspergillus Infections

Department of Internal Medicine, Pneumonology and Allergology, Medical University of Warsaw, 02-097 Warsaw, Poland

Received 20 April 2011; Accepted 4 October 2011

Academic Editor: K. Kayser

Copyright © 2011 Rafal Krenke and Elzbieta M. Grabczak. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Al-Alawi, C. F. Ryan, J. D. Flint, and N. L. Müller, “Aspergillus-related lung disease,” Canadian Respiratory Journal, vol. 12, no. 7, pp. 377–387, 2005. View at Google Scholar
  2. O. S. Zmeili and A. O. Soubani, “Pulmonary aspergillosis: a clinical update,” Quarterly Journal of Medicine, vol. 100, no. 6, pp. 317–334, 2007. View at Publisher · View at Google Scholar · View at PubMed
  3. E. Roilides, H. Katsifa, and T. J. Walsh, “Pulmonary host defences against Aspergillus fumigatus,” Research in Immunology, vol. 149, no. 4-5, pp. 454–460, 1998. View at Publisher · View at Google Scholar
  4. M. Farouk Allam, A. Serrano del Castillo, C. Díaz-Molina, and R. Fernández-Crehuet Navajas, “Invasive pulmonary aspergillosis: identification of risk factors,” Scandinavian Journal of Infectious Diseases, vol. 34, no. 11, pp. 819–822, 2002. View at Publisher · View at Google Scholar
  5. K. J. Hartemink, M. A. Paul, J. J. Spijkstra, A. R. J. Girbes, and K. H. Polderman, “Immunoparalysis as a cause for invasive aspergillosis?” Intensive Care Medicine, vol. 29, no. 11, pp. 2068–2071, 2003. View at Publisher · View at Google Scholar · View at PubMed
  6. O. P. Sharma and R. Chwogule, “Many faces of pulmonary aspergillosis,” European Respiratory Journal, vol. 12, no. 3, pp. 705–715, 1998. View at Publisher · View at Google Scholar
  7. F. Reichenberger, J. M. Habicht, A. Gratwohl, and M. Tamm, “Diagnosis and treatment of invasive pulmonary aspergillosis in neutropenic patients,” European Respiratory Journal, vol. 19, no. 4, pp. 743–755, 2002. View at Publisher · View at Google Scholar
  8. D. M. Geiser, M. A. Klich, J. C. Frisvad, S. W. Peterson, J. Varga, and R. A. Samson, “The current status of species recognition and identification in Aspergillus,” Studies in Mycology, vol. 59, pp. 1–10, 2007. View at Publisher · View at Google Scholar · View at PubMed
  9. T. F. Patterson, W. R. Kirkpatrick, M. White et al., “Invasive aspergillosis. Disease spectrum, treatment practices, and outcomes. I3 Aspergillus Study Group,” Medicine, vol. 79, no. 4, pp. 250–260, 2000. View at Publisher · View at Google Scholar
  10. K. A. Marr, R. A. Carter, F. Crippa, A. Wald, and L. Corey, “Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients,” Clinical Infectious Diseases, vol. 34, no. 7, pp. 909–917, 2002. View at Publisher · View at Google Scholar · View at PubMed
  11. G. Maschmeyer, A. Haas, and O. A. Cornely, “Invasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients,” Drugs, vol. 67, no. 11, pp. 1567–1601, 2007. View at Publisher · View at Google Scholar
  12. D. Karnak, R. K. Avery, T. R. Gildea, D. Sahoo, and A. C. Mehta, “Endobronchial fungal disease: an under-recognized entity,” Respiration, vol. 74, no. 1, pp. 88–104, 2006. View at Publisher · View at Google Scholar · View at PubMed
  13. A. O. Soubani and P. H. Chandrasekar, “The clinical spectrum of pulmonary aspergillosis,” Chest, vol. 121, no. 6, pp. 1988–1999, 2002. View at Publisher · View at Google Scholar
  14. M. R. Kramer, D. W. Denning, S. E. Marshall et al., “Ulcerative tracheobronchitis after lung transplantation: a new form of invasive aspergillosis,” American Review of Respiratory Disease, vol. 144, no. 3 I, pp. 552–556, 1991. View at Google Scholar
  15. D. W. Denning, “Commentary: unusual manifestations of aspergillosis,” Thorax, vol. 50, no. 7, pp. 812–813, 1995. View at Google Scholar
  16. D. W. Denning, “Invasive aspergillosis,” Clinical Infectious Diseases, vol. 26, no. 4, pp. 781–803, 1998. View at Google Scholar
  17. N. Patel, A. Saleh, S. Raoof, M. Gudi, L. George, and U. B.S. Prakash, “Tracheobronchial manifestations of aspergillosis,” Journal of Bronchology, vol. 17, no. 1, pp. 45–53, 2010. View at Publisher · View at Google Scholar
  18. J. S. Kim, Y. Rhee, S. M. Kang et al., “A case of endobronchial aspergilloma,” Yonsei Medical Journal, vol. 41, no. 3, pp. 422–425, 2000. View at Google Scholar
  19. K. Patterson and M. E. Strek, “Allergic bronchopulmonary aspergillosis,” Proceedings of the American Thoracic Society, vol. 7, no. 3, pp. 237–244, 2010. View at Google Scholar
  20. R. Agarwal, “Allergic bronchopulmonary aspergillosis,” Chest, vol. 135, no. 3, pp. 805–826, 2009. View at Publisher · View at Google Scholar · View at PubMed
  21. P. A. B. Wark, M. J. Hensley, N. Saltos et al., “Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: a randomized controlled trial,” Journal of Allergy and Clinical Immunology, vol. 111, no. 5, pp. 952–957, 2003. View at Publisher · View at Google Scholar
  22. R. L. Kradin and E. J. Mark, “The pathology of pulmonary disorders due to Aspergillus spp,” Archives of Pathology and Laboratory Medicine, vol. 132, no. 4, pp. 606–614, 2008. View at Google Scholar
  23. R. R. SHAW, “Mucoid impaction of the bronchi,” The Journal of Thoracic Surgery, vol. 22, no. 2, pp. 149–163, 1951. View at Google Scholar
  24. S. Martinez, L. E. Heyneman, H. P. McAdams, S. E. Rossi, C. S. Restrepo, and A. Eraso, “Mucoid impactions: finger-in-glove sign and other CT and radiographic features,” Radiographics, vol. 28, no. 5, pp. 1369–1382, 2008. View at Publisher · View at Google Scholar · View at PubMed
  25. V. Maurya, H. C. Gugnani, P. U. Sarma, T. Madan, and A. Shah, “Sensitization to Aspergillus antigens and occurrence of allergic bronchopulmonary aspergillosis in patients with asthma,” Chest, vol. 127, no. 4, pp. 1252–1259, 2005. View at Publisher · View at Google Scholar · View at PubMed
  26. A. Shah, “Aspergillus-associated hypersensitivity respiratory disorders,” The Indian Journal of Chest Diseases & Allied Sciences, vol. 50, no. 1, pp. 117–128, 2008. View at Google Scholar
  27. D. W. Denning, S. E. Follansbee, M. Scolaro, S. Norris, H. Edelstein, and D. A. Stevens, “Pulmonary aspergillosis in the acquired immunodeficiency syndrome,” The New England Journal of Medicine, vol. 324, no. 10, pp. 654–662, 1991. View at Google Scholar
  28. W. T. Miller Jr., G. J. Sais, I. Frank, W. B. Gefter, J. M. Aronchick, and W. T. Miller, “Pulmonary aspergillosis in patients with AIDS: clinical and radiographic correlations,” Chest, vol. 105, no. 1, pp. 37–44, 1994. View at Google Scholar
  29. M. Hummel, S. Schuler, S. Hempel, W. Rees, and R. Hetzer, “Obstructive bronchial aspergillosis after heart transplantation,” Mycoses, vol. 36, no. 11-12, pp. 425–428, 1993. View at Google Scholar
  30. D. R. Nunley, A. A. Gal, J. D. Vega, C. Perlino, P. Smith, and E. Clinton Lawrence, “Saprophytic fungal infections and complications involving the bronchial anastomosis following human lung transplantation,” Chest, vol. 122, no. 4, pp. 1185–1191, 2002. View at Publisher · View at Google Scholar
  31. D. W. Denning and D. A. Stevens, “Antifungal and surgical treatment of invasive aspergillosis: review of 2,121 published cases,” Reviews of Infectious Diseases, vol. 12, no. 6, pp. 1147–1201, 1990. View at Google Scholar
  32. M. Noppen, I. Claes, B. Maillet, M. Meysman, I. Monsieur, and W. Vincken, “Three cases of bronchial stump aspergillosis: unusual clinical presentations and beneficial effect of oral itraconazole,” European Respiratory Journal, vol. 8, no. 3, pp. 477–480, 1995. View at Google Scholar
  33. J. Roig, J. Ruiz, X. Puig, A. Carreres, and J. Morera, “Bronchial stump aspergillosis four years after lobectomy,” Chest, vol. 104, no. 1, pp. 295–296, 1993. View at Google Scholar
  34. J. P. Le Rochais, P. Icard, T. Simon, P. Poirier, and C. Evrard, “Bronchial stump aspergillosis,” Annals of Thoracic Surgery, vol. 70, no. 1, pp. 302–304, 2000. View at Publisher · View at Google Scholar
  35. L. Kumar, M. Singh, S. K. Mitra, and C. K. Bannerjee, “Superadded aspergillosis on carcinoid bronchial adenoma leading to delayed diagnosis,” Postgraduate Medical Journal, vol. 66, no. 781, pp. 938–939, 1990. View at Google Scholar
  36. P. M. Logan, S. L. Primack, R. R. Miller, and N. L. Muller, “Invasive aspergillosis of the airways: radiographic, CT, and pathologic findings,” Radiology, vol. 193, no. 2, pp. 383–388, 1994. View at Google Scholar
  37. C. A. Kemper, J. S. Hostetler, S. E. Follansbee et al., “Ulcerative and plaque-like tracheobronchitis due to infection with Aspergillus in patients with AIDS,” Clinical Infectious Diseases, vol. 17, no. 3, pp. 344–352, 1993. View at Google Scholar
  38. M. I. Ahn, S. H. Park, J. A. Kim, M. S. Kwon, and Y. H. Park, “Pseudomembranous necrotizing bronchial aspergillosis,” British Journal of Radiology, vol. 73, no. 865, pp. 73–75, 2000. View at Google Scholar
  39. S. Irani, T. Brack, and E. W. Russi, “Tracheobronchial mucosal lesions in a 40-year-old bone marrow recipient,” Respiration, vol. 70, no. 3, p. 302, 2003. View at Publisher · View at Google Scholar · View at PubMed
  40. S. M. Chang, H. T. Kuo, F. J. Lin, C. Y. Tzen, and C. Y. Sheu, “Pseudomembranous tracheobronchitis caused by Aspergillus in immunocompromised patients,” Scandinavian Journal of Infectious Diseases, vol. 37, no. 11-12, pp. 937–942, 2005. View at Publisher · View at Google Scholar · View at PubMed
  41. J. Franco, C. Muñoz, B. Vila, and J. Marín, “Pseudomembranous invasive tracheobronchial aspergillosis,” Thorax, vol. 59, no. 5, p. 452, 2004. View at Publisher · View at Google Scholar
  42. A. Mohan, R. Guleria, S. Mukhopadhyaya, C. Das, A. Nayak, and S. K. Sharma, “Invasive tracheobronchial aspergillosis in an immunocompetent person,” American Journal of the Medical Sciences, vol. 329, no. 2, pp. 107–109, 2005. View at Publisher · View at Google Scholar
  43. S. Ascioglu, J. H. Rex, B. De Pauw et al., “Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus,” Clinical Infectious Diseases, vol. 34, no. 1, pp. 7–14, 2002. View at Publisher · View at Google Scholar · View at PubMed
  44. B. De Pauw, T. J. Walsh, J. P. Donnelly et al., “Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group,” Clinical Infectious Diseases, vol. 46, no. 12, pp. 1813–1821, 2008. View at Publisher · View at Google Scholar · View at PubMed
  45. S. Tasci, A. Glasmacher, S. Lentini et al., “Pseudomembranous and obstructive Aspergillus tracheobronchitis—optimal diagnostic strategy and outcome,” Mycoses, vol. 49, no. 1, pp. 37–42, 2006. View at Publisher · View at Google Scholar · View at PubMed
  46. N. Wu, Y. Huang, Q. Li, C. Bai, H. D. Huang, and X. P. Yao, “Isolated invasive Aspergillus tracheobronchitis: a clinical study of 19 cases,” Clinical Microbiology and Infection, vol. 16, no. 6, pp. 689–695, 2010. View at Publisher · View at Google Scholar · View at PubMed
  47. B. Mehrad, G. Paciocco, F. J. Martinez, T. C. Ojo, M. D. Iannettoni, and J. P. Lynch, “Spectrum of Aspergillus infection in lung transplant recipients: case series and review of the literature,” Chest, vol. 119, no. 1, pp. 169–175, 2001. View at Publisher · View at Google Scholar
  48. A. Solé, P. Morant, M. Salavert et al., “Aspergillus infections in lung transplant recipients: risk factors and outcome,” Clinical Microbiology and Infection, vol. 11, no. 5, pp. 359–365, 2005. View at Publisher · View at Google Scholar · View at PubMed
  49. S. D. Nathan, A. F. Shorr, M. E. Schmidt, and N. A. Burton, “Aspergillus and endobronchial abnormalities in lung transplant recipients,” Chest, vol. 118, no. 2, pp. 403–407, 2000. View at Google Scholar
  50. N. Singh and S. Husain, “Aspergillus infections after lung transplantation: clinical differences in type of transplant and implications for management,” Journal of Heart and Lung Transplantation, vol. 22, no. 3, pp. 258–266, 2003. View at Publisher · View at Google Scholar
  51. M. Helmi, R. B. Love, D. Welter, R. D. Cornwell, and K. C. Meyer, “Aspergillus infection in lung transplant recipients with cystic fibrosis: risk factors and outcomes comparison to other types of transplant recipients,” Chest, vol. 123, no. 3, pp. 800–808, 2003. View at Publisher · View at Google Scholar
  52. A. Vadnerkar, C. J. Clancy, U. Celik et al., “Impact of mold infections in explanted lungs on outcomes of lung transplantation,” Transplantation, vol. 89, no. 2, pp. 253–260, 2010. View at Publisher · View at Google Scholar · View at PubMed
  53. P. A. Flume, T. M. Egan, L. J. Paradowski, F. C. Detterbeck, J. T. Thompson, and J. R. Yankaskas, “Infectious complications of lung transplantation: impact of cystic fibrosis,” American Journal of Respiratory and Critical Care Medicine, vol. 149, no. 6, pp. 1601–1607, 1994. View at Google Scholar
  54. D. R. Nunley, N. P. Ohori, W. F. Grgurich et al., “Pulmonary aspergillosis in cystic fibrosis lung transplant recipients,” Chest, vol. 114, no. 5, pp. 1321–1329, 1998. View at Google Scholar
  55. E. J. Kwak, S. Husain, A. Obman et al., “Efficacy of galactomannan antigen in the Platelia Aspergillus enzyme immunoassay for diagnosis of invasive aspergillosis in liver transplant recipients,” Journal of Clinical Microbiology, vol. 42, no. 1, pp. 435–438, 2004. View at Publisher · View at Google Scholar
  56. S. Husain, D. L. Paterson, S. M. Studer et al., “Aspergillus galactomannan antigen in the bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in lung transplant recipients,” Transplantation, vol. 83, no. 10, pp. 1330–1336, 2007. View at Publisher · View at Google Scholar · View at PubMed
  57. M. R. Aerni, J. G. Parambil, M. S. Allen, and J. P. Utz, “Nontraumatic disruption of the fibrocartilaginous trachea: causes and clinical outcomes,” Chest, vol. 130, no. 4, pp. 1143–1149, 2006. View at Publisher · View at Google Scholar · View at PubMed
  58. S. Husain, D. Zaldonis, S. Kusne, E. J. Kwak, D. L. Paterson, and K. R. McCurry, “Variation in antifungal prophylaxis strategies in lung transplantation,” Transplant Infectious Disease, vol. 8, no. 4, pp. 213–218, 2006. View at Publisher · View at Google Scholar · View at PubMed
  59. A. Solé and M. Salavert, “Fungal infections after lung transplantation,” Current Opinion in Pulmonary Medicine, vol. 15, no. 3, pp. 243–253, 2009. View at Publisher · View at Google Scholar · View at PubMed
  60. R. Zaragoza, J. Pemán, M. Salavert et al., “Multidisciplinary approach to the treatment of invasive fungal infections in adult patients. Prophylaxis, empirical, preemptive or targeted therapy, which is the best in the different hosts?” Therapeutics and Clinical Risk Management, vol. 4, no. 6, pp. 1261–1280, 2008. View at Google Scholar
  61. A. Solé, “Invasive fungal infections in lung transplantation: role of aerosolised amphotericin B,” International Journal of Antimicrobial Agents, vol. 32, no. 2, pp. S161–S165, 2008. View at Publisher · View at Google Scholar
  62. J. M. Borro, A. Solé, M. de la Torre et al., “Efficiency and safety of inhaled amphotericin B lipid complex (Abelcet) in the prophylaxis of invasive fungal infections following lung transplantation,” Transplantation Proceedings, vol. 40, no. 9, pp. 3090–3093, 2008. View at Publisher · View at Google Scholar · View at PubMed
  63. V. Monforte, P. Ussetti, J. Gavaldà et al., “Feasibility, tolerability, and outcomes of nebulized liposomal amphotericin B for Aspergillus infection prevention in lung transplantation,” Journal of Heart and Lung Transplantation, vol. 29, no. 5, pp. 523–530, 2010. View at Publisher · View at Google Scholar · View at PubMed
  64. A. Clarke, J. Skelton, and R. S. Fraser, “Fungal tracheobronchitis. Report of 9 cases and review of the literature,” Medicine, vol. 70, no. 1, pp. 1–14, 1991. View at Google Scholar
  65. J. M. Sancho, J. M. Ribera, A. Rosell, C. Muñoz, and E. Feliu, “Unusual invasive bronchial aspergillosis in a patient with acute lymphoblastic leukemia,” Haematologica, vol. 82, no. 6, pp. 701–702, 1997. View at Google Scholar
  66. R. Krenke, A. Kołkowska-Leśniak, G. Pałynyczko, M. Prochorec-Sobieszek, and L. Konopka, “Ulcerative and pseudomembranous Aspergillus tracheobronchitis in a patient with acute myeloid leukemia,” International Journal of Hematology, vol. 89, no. 3, pp. 257–258, 2009. View at Publisher · View at Google Scholar · View at PubMed
  67. J. M. Arriero, E. Chiner, J. Marco, M. J. Mayol, and M. Serna, “Simultaneous obstructing and pseudomembranous necrotizing tracheobronchitis due to Aspergillus flavus,” Clinical Infectious Diseases, vol. 26, no. 6, pp. 1464–1465, 1998. View at Google Scholar
  68. D. Buchheidt, A. Weiss, S. Reiter, G. Hartung, and R. Hehlmann, “Pseudomembranous tracheobronchial aspergillosis: a rare manifestation of invasive aspergillosis in a non-neutropenic patient with Hodgkin's disease,” Mycoses, vol. 46, no. 1-2, pp. 51–55, 2003. View at Publisher · View at Google Scholar
  69. S. Van Assen, G. P. Bootsma, P. E. Verweij, J. P. Donnelly, and J. M. M. Racemakers, “Aspergillus tracheobronchitis after allogeneic bone marrow transplantation,” Bone Marrow Transplantation, vol. 26, no. 10, pp. 1131–1132, 2000. View at Google Scholar
  70. U. Machida, M. Kami, Y. Kanda et al., “Aspergillus tracheobronchitis after allogeneic bone marrow transplantation,” Bone Marrow Transplantation, vol. 24, no. 10, pp. 1145–1149, 1999. View at Google Scholar
  71. R. F. Casal, R. Adachi, C. A. Jimenez, M. Sarkiss, R. C. Morice, and G. A. Eapen, “Diagnosis of invasive aspergillus tracheobronchitis facilitated by endobronchial ultrasound-guided transbronchial needle aspiration: a case report,” Journal of Medical Case Reports, vol. 3, article 9290, 2009. View at Publisher · View at Google Scholar · View at PubMed
  72. C. Routsi, P. Kaltsas, E. Bessis, D. Rontogianni, S. Kollias, and C. Roussos, “Airway obstruction and acute respiratory failure due to Aspergillus tracheobronchitis,” Critical Care Medicine, vol. 32, no. 2, pp. 580–582, 2004. View at Publisher · View at Google Scholar · View at PubMed
  73. S. A. Garofano, D. E. Stover, G. W. Freeberg, and D. S. Klimstra, “Necrotizing aspergillus tracheobronchitis: a case associated with fatal hemorrhage following endobronchial biopsy,” Journal Of Bronchology, vol. 1, pp. 299–303, 1994. View at Google Scholar
  74. N. T. Berlinger and T. J. Freeman, “Acute airway obstruction due to necrotizing tracheobronchial spergillosis in immunocompromised patients: a new clinical entity,” Annals of Otology, Rhinology and Laryngology, vol. 98, no. 9, pp. 718–720, 1989. View at Google Scholar
  75. A. Ramos, J. Segovia, M. Gómez-Bueno et al., “Pseudomembranous aspergillus tracheobronchitis in a heart transplant recipient: case report,” Transplant Infectious Disease, vol. 12, no. 1, pp. 60–63, 2010. View at Publisher · View at Google Scholar · View at PubMed
  76. F. G. De Rosa, P. Terragni, D. Pasero et al., “Combination antifungal treatment of pseudomembranous tracheobronchial invasive aspergillosis: a case report,” Intensive Care Medicine, vol. 35, no. 9, pp. 1641–1643, 2009. View at Publisher · View at Google Scholar · View at PubMed
  77. T. J. Walsh, E. J. Anaissie, D. W. Denning et al., “Treatment of aspergillosis: clinical practice guidelines of the infectious diseases society of America,” Clinical Infectious Diseases, vol. 46, no. 3, pp. 327–360, 2008. View at Publisher · View at Google Scholar · View at PubMed
  78. A. Moreno, M. Perez-Elías, J. Casado et al., “Role of antiretroviral therapy in long-term survival of patients with AIDS-related pulmonary aspergillosis,” European Journal of Clinical Microbiology and Infectious Diseases, vol. 19, no. 9, pp. 688–693, 2000. View at Google Scholar
  79. N. K. Pervez, J. Kleinerman, M. Kattan et al., “Pseudomembranous necrotizing bronchial aspergillosis. A variant of invasive aspergillosis in a patient with hemophilia and acquired immune deficiency syndrome,” American Review of Respiratory Disease, vol. 131, no. 6, pp. 961–963, 1985. View at Google Scholar
  80. E. Roilides, A. Holmes, C. Blake, P. A. Pizzo, and T. J. Walsh, “Defective antifungal activity of monocyte-derived macrophages from human immunodeficiency virus-infected children against Aspergillus fumigatus,” Journal of Infectious Diseases, vol. 168, no. 6, pp. 1562–1565, 1993. View at Google Scholar
  81. I. D. Conte, G. Riva, R. Obert et al., “Tracheobronchial aspergillosis in a patient with AIDS treated with aerosolized amphotericin B combined with itraconazole,” Mycoses, vol. 39, no. 9-10, pp. 371–374, 1996. View at Google Scholar
  82. E. Mylonakis, T. F. Barlam, T. Flanigan, and J. D. Rich, “Pulmonary aspergillosis and invasive disease in AIDS: review of 342 cases,” Chest, vol. 114, no. 1, pp. 251–262, 1998. View at Google Scholar
  83. M. A. Judson and S. A. Sahn, “Endobronchial lesions in HIV-infected individuals,” Chest, vol. 105, no. 5, pp. 1314–1323, 1994. View at Google Scholar
  84. S. E. Lee, J. H. Song, J. W. Shin et al., “A case of pseudomembranous necrotizing bronchial aspergillosis in an old age host,” Tuberculosis and Respiratory Diseases, vol. 63, no. 3, pp. 278–282, 2007. View at Google Scholar
  85. H. J. Oh, H. R. Kim, K. E. Hwang et al., “Case of pseudomembranous necrotizing tracheobronchial aspergillosis in an immunocompetent host,” Korean Journal of Internal Medicine, vol. 21, no. 4, pp. 279–282, 2006. View at Google Scholar
  86. S. De and P. Desikan, “Unusual cause of chronic cough in an immunocompetent host,” Journal of Bronchology, vol. 16, no. 1, pp. 61–62, 2009. View at Publisher · View at Google Scholar
  87. P. Pornsuriyasak, S. Murgu, and H. Colt, “Pseudomembranous aspergillus tracheobronchitis superimposed on post-tuberculosis tracheal stenosis,” Respirology, vol. 14, no. 1, pp. 144–147, 2009. View at Publisher · View at Google Scholar · View at PubMed
  88. T. Niimi, M. Kajita, and H. Saito, “Necrotizing bronchial aspergillosis in a patient receiving neoadjuvant chemotherapy for non-small cell lung carcinoma,” Chest, vol. 100, no. 1, pp. 277–279, 1991. View at Google Scholar
  89. A. Al-Alawi and F. Ryan, “Aspergillus pseudomembranous tracheobronchitis complicating treatment of COPD exacerbations,” Kuwait Medical Journal, vol. 39, pp. 184–187, 2007. View at Google Scholar
  90. M. Ruhnke, E. Eichenauer, J. Searle, and F. Lippek, “Fulminant tracheobronchial and pulmonary aspergillosis complicating imported Plasmodium falciparum malaria in an apparently immunocompetent woman,” Clinical Infectious Diseases, vol. 30, no. 6, pp. 938–940, 2000. View at Publisher · View at Google Scholar · View at PubMed
  91. P. H. Kuo, L. N. Lee, P. C. Yang, Y. C. Chen, and K. T. Luh, “Aspergillus laryngotracheobronchitis presenting as stridor in a patient with peripheral T cell lymphoma,” Thorax, vol. 51, no. 8, pp. 869–870, 1996. View at Google Scholar
  92. S. Tasci, H. Schäfer, S. Ewig, B. Lüderitz, and H. Zhou, “Pseudomembraneous Aspergillus fumigatus tracheobronchitis causing life-threatening tracheobronchial obstruction in a mechanically ventilated patient,” Intensive Care Medicine, vol. 26, no. 1, pp. 143–144, 2000. View at Google Scholar
  93. L. P. Koh, Y. T. Goh, Y. C. Linn, J. Hwang, and P. Tan, “Pseudomembranous tracheobronchitis caused by Aspergillus in a patient after peripheral blood stem cell transplantation,” Annals of the Academy of Medicine Singapore, vol. 29, no. 4, pp. 531–533, 2000. View at Google Scholar
  94. C. Routsi, E. Platsouka, A. Prekates, D. Rontogianni, O. Paniara, and C. Roussos, “Aspergillus bronchitis causing atelectasis and acute respiratory failure in an immunocompromised patient,” Infection, vol. 29, no. 4, pp. 243–244, 2001. View at Publisher · View at Google Scholar
  95. M. Onozawa, S. Takahashi, H. Kanamori et al., “Pseudomembranous tracheobronchial aspergillosis,” Internal Medicine Journal, vol. 39, no. 1, pp. 65–66, 2009. View at Publisher · View at Google Scholar · View at PubMed