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TheScientificWorldJOURNAL
Volume 11 (2011), Pages 736-741
http://dx.doi.org/10.1100/tsw.2011.57
Short Communication

Sensory Gating Scales and Premonitory Urges in Tourette Syndrome

1Department of Psychiatry, UCSD School of Medicine, La Jolla, CA, USA
2Departamento de Psiquiatria da Faculdade de Medicina da USP, Sao Paulo, SP, Brazil

Received 17 June 2010; Revised 28 January 2011; Accepted 7 February 2011

Academic Editor: John Weisz

Copyright © 2011 Ashley N. Sutherland Owens et al.

Abstract

Sensory and sensorimotor gating deficits characterize both Tourette syndrome (TS) and schizophrenia. Premonitory urges (PU) in TS can be assessed with the University of Sao Paulo Sensory Phenomena Scale (USP-SPS) and the Premonitory Urge for Tics Scale (PUTS). In 40 subjects (TS: n = 18; healthy comparison subjects [HCS]: n = 22), we examined the relationship between PU scores and measures of sensory gating using the USP-SPS, PUTS, Sensory Gating Inventory (SGI), and Structured Interview for Assessing Perceptual Anomalies (SIAPA), as well symptom severity scales. SGI, but not SIAPA, scores were elevated in TS subjects (p < 0.0003). In TS subjects, USP-SPS and PUTS scores correlated significantly with each other, but not with the SGI or SIAPA; neither PU nor sensory gating scales correlated significantly with symptom severity. TS subjects endorse difficulties in sensory gating and the SGI may be valuable for studying these clinical phenomena.