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The Scientific World Journal
Volume 2012, Article ID 102829, 3 pages
Research Article

Parvovirus B19 Infection and Severe Anemia in Renal Transplant Recipients

1Clinical Pathology Laboratory, Santa Maria Goretti Hospital, AUSL Latina, 04100 Latina, Italy
2CEREM, Experimental Zooprophylactic Institute of Umbria and Marche (IZSUM), 60126 Ancona, Italy
3Kidney Transplant Unit, Santa Maria Goretti Hospital, AUSL Latina, 04100 Latina, Italy

Received 27 October 2011; Accepted 22 December 2011

Academic Editor: Chitra Hosing

Copyright © 2012 Antonio Carraturo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Kidney transplant (KT) recipients can develop symptomatic Parvovirus (PV) B19 infections, frequently associated with persistent anemia. The aim of this study was to evaluate the prevalence and clinical significance of PV B19 infection in anemic and non-anemic KT patients. Overall, out of 64 patients monitored for the presence of PV B19 by real-time PCR, 2 (3.12%) had an active PV B19 infection, in absence of other viral coinfections. The 2 cases occurred in nonanemic kidney transplant patients group (2/50, 4%), while none of the anemic transplant patients (0/14) was found to suffer from this infection. Moreover, patients affected by active PV B19 infection showed viral loads not exceeding 1 × 1 0 5 genome copies/reaction. In conclusion, in this study, PV B19 infection was not common in renal transplant population and wasn’t associated with severe anemia.