Comparative Analysis of Apoptotic Resistance of Mesenchymal Stem Cells Isolated from Human Bone Marrow and Adipose Tissue

Figure 1

Representative fields showing hBM- and hAT-MSCs morphologies for different passages. (a-b) hBM-MSCs in culture. During the onset of culture P₀: 12th day (a), P₂: 1st day (b), and P₃: 7th day (c). MSCs attached to the culture flasks sparsely and displayed a fibroblast-like, spindle-shaped morphology during the initial days of incubation. After 5–7 days of incubation, proliferation started and the cells gradually grew into small colonies (a). After the next passages, most of these MSCs exhibited large, flattened morphology (b, c). (c-d) Representative fields showing hAT-MSCs morphologies for different passages ((c) P₀: 12th day, (d) P₂: 4th day, and (e) P₃: 6th day). hAT-MSCs were observed to appear morphologically very similar to hBM-MSCs.

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