Holotranscobalamin Is a Useful Marker of Vitamin B12 Deficiency in Alcoholics

Table 1

Alcoholic patients: sex, age, hematologic, and metabolic characteristics; 𝑁=22 (M 22); mean age (range): 60 years (35–82).

	Normal value	Range	Median
Hb g/dL	12.5–16.5	6–15.3	11.7
MCV fL	80–98	74–110	98.6
Ferritin ng/mL	33–322	48–4841	551
AST U/l	<37	11–251	43
ALT U/l	<40	12–305	34
GGT U/l	5–37	31–2452	120
Cbl pg/mL	200–1100	196–3768	480
Folate serum ng/mL	3.1–24	0.3–8.5	4.1
Folate RBC ng/mL	342–786	147–1193	400
HoloTC pmol/L	>35	21–640	96

Hb: hemoglobin; MCV: mean corpuscular volume; Ferritin: serum ferritin; AST: aspartate aminotransferase; ALT: alanine aminotransferase; GGT: gamma-glutamyl transpeptidase; Cbl: cobalamin; RBC: red blood cells; HoloTC: holotranscobalamin.