Table of Contents Author Guidelines Submit a Manuscript
The Scientific World Journal
Volume 2012, Article ID 135283, 9 pages
Research Article

Comparing Health-Related Quality of Life of Cancer Patients under Chemotherapy and of Their Caregivers

1Second Department of Internal Medicine, Medical School, Attikon University General Hospital, P.C. 12462 Athens, Greece
2Faculty of Social Sciences, Hellenic Open University, P.C. 26222 Patras, Greece
3Department of Pathology, A. Fleming General Hospital, P.C. 15127 Athens, Greece

Received 28 October 2011; Accepted 21 December 2011

Academic Editors: D. A. Altomare and I. Turesson

Copyright © 2012 Ioannis Vrettos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. Cancer is a major disorder physically and psychologically affecting both patients and their caregivers. In this study, health-related quality of life (HRQoL) of patient-caregiver dyads during the period of chemotherapy was assessed. Material and Methods. Two hundred twenty-two cancer patient-caregiver dyads were enrolled in the study, which was conducted from October 2008 to March 2009. HRQoL was evaluated with EQ-5D. Results. The mean age of the sample was 57.4 and 48.9 for patients and caregivers, respectively. The EQ-5D descriptive system indicates that female patients more frequently experience anxiety and depression than male patients. Male and higher-education caregivers had higher VAS scores, while demographic factors did not seem to influence patients’ HRQoL. Anxiety and depression of caregivers were correlated with patients’ problems in self-care and usual activities. Conclusions. Quality of life is highly influenced during the period of chemotherapy for both patients and caregivers and is often under reported. Interventions that can improve HRQoL, especially in the domain of mental health for both cancer patients and their caregivers, need to be implemented.