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The Scientific World Journal
Volume 2012, Article ID 165258, 6 pages
Research Article

Docking Studies, Synthesis, Characterization and Evaluation of Their Antioxidant and Cytotoxic Activities of Some Novel Isoxazole-Substituted 9-Anilinoacridine Derivatives

Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS University, Tamilnadu Ootacamund 643001, India

Received 19 October 2011; Accepted 10 January 2012

Academic Editor: Mine Ozyazici

Copyright © 2012 R. Kalirajan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • R. Kalirajan, Vivek Kulshrestha, S. Sankar, and S. Jubie, “Docking studies, synthesis, characterization of some novel oxazine substituted 9-anilinoacridine derivatives and evaluation for their antioxidant and anticancer activities as topoisomerase II inhibitors,” European Journal Of Medicinal Chemistry, vol. 56, pp. 217–224, 2012. View at Publisher · View at Google Scholar
  • Selvaraj Jubie, Rajagopal Kalirajan, Sundaram Sankar, and Byran Gowramma, “Molecular docking studies and in-silico ADMET screening of some novel oxazine substituted 9-anilinoacridines as topoisomerase II inhibitors,” Indian Journal of Pharmaceutical Education and Research, vol. 51, no. 1, pp. 110–115, 2017. View at Publisher · View at Google Scholar
  • Khaled R.A. Abdellatif, Mohamed A. Abdelgawad, Heba A. H. Elshemy, Nesma M. Kahk, and Dalia M. El Amir, “Design, synthesis, antioxidant and anticancer activity of new coumarin derivatives linked with thiazole, isoxazole or pyrazole moiety,” Letters in Drug Design and Discovery, vol. 14, no. 7, pp. 773–781, 2017. View at Publisher · View at Google Scholar
  • Neetu Agrawal, and Pradeep Mishra, “The synthetic and therapeutic expedition of isoxazole and its analogs,” Medicinal Chemistry Research, 2018. View at Publisher · View at Google Scholar
  • Rawny Galdino Gouveia, Amélia Galdino Ribeiro, Miguel Ângelo Santos Pinheiro Segundo, Jamerson Ferreira de Oliveira, Maria do Carmo Alves de Lima, Túlio Ricardo Couto de Lima Souza, Sinara Mônica Vitalino de Almeida, and Ricardo Olímpio de Moura, “Synthesis, DNA and protein interactions and human topoisomerase inhibition of novel Spiro-acridine derivatives,” Bioorganic & Medicinal Chemistry, 2018. View at Publisher · View at Google Scholar
  • Olla Sharhan, Thorsten Heidelberg, Najiahah Mohd Hashim, Abbas Abdulameer Salman, Hapipah Mohd Ali, and Soher Nagi Jayash, “Synthesis and biological study of acridine-based imidazolium salts,” RSC Advances, vol. 8, no. 68, pp. 38995–39004, 2018. View at Publisher · View at Google Scholar