The Scientific World Journal / 2012 / Article / Tab 1 / Research Article
Docking Studies, Synthesis, Characterization and Evaluation of Their Antioxidant and Cytotoxic Activities of Some Novel Isoxazole-Substituted 9-Anilinoacridine Derivatives Table 1 Antioxidant activity of synthesized compounds 4a–j and 5a–j by DPPH method, reducing power assay and total antioxidant capacity method.
S. No Cpd. Code IC50 values for DPPH method (μ g/mL) IC50 values for reducing power assay (μ g/mL) IC50 values for TAC (μ g/mL) (1) 4a >1000 >500 >500 (2) 4b >1000 >500 >500 (3) 4c >1000 >500 >500 (4) 4d >1000 >500 >500 (5) 4e >1000 >500 >500 (6) 4f >1000 >500 >500 (7) 4g >1000 >500 >500 (8) 4h >1000 >500 >500 (9) 4i >1000 >500 >500 (10) 4j >1000 >500 >500 (11) 5a
1
8
.
3
0
±
0
.
4
5
8
3
3
4
.
1
7
±
0
.
5
7
8
3
8
9
.
6
0
±
0
.
7
7
6
7
(12) 5b
5
0
.
2
3
±
1
.
0
4
8
6
8
.
2
7
±
0
.
5
6
0
8
1
2
2
.
0
±
1
.
0
4
4
(13) 5c
1
7
.
5
3
±
0
.
0
8
8
2
2
.
1
3
±
0
.
5
0
4
4
9
2
.
8
0
±
0
.
9
0
7
4
(14) 5d
1
4
.
2
0
±
0
.
1
5
2
8
2
6
.
4
3
±
0
.
5
6
9
6
8
1
.
8
3
±
0
.
2
4
0
4
(15) 5e
3
3
.
2
0
±
1
.
3
2
3
4
3
.
3
7
±
0
.
5
9
2
5
1
1
1
.
8
±
0
.
8
8
1
9
(16) 5f
1
2
.
6
7
±
0
.
1
2
0
2
2
9
.
5
0
±
0
.
8
7
1
8
9
1
.
4
3
±
0
.
2
4
0
4
(17) 5g
2
7
.
0
0
±
0
.
8
6
6
0
4
7
.
0
3
±
1
.
0
3
5
1
3
2
.
3
±
0
.
8
0
9
0
(18) 5h
2
8
.
2
0
±
0
.
3
4
6
4
3
7
.
3
0
±
0
.
4
6
1
9
7
5
.
4
3
±
0
.
2
4
0
4
(19) 5i
1
3
.
6
3
±
0
.
1
7
6
4
1
9
.
2
3
±
0
.
4
6
6
7
9
5
.
4
3
±
0
.
2
4
0
4
(20) 5j
1
6
.
3
0
±
0
.
5
5
6
8
2
0
.
5
3
±
1
.
0
0
4
6
5
.
9
7
±
0
.
5
2
0
7
(21) Standard ascorbic acid
1
8
.
6
0
±
1
.
0
3
9
2
4
.
7
7
±
0
.
2
4
0
4
8
6
.
1
7
±
0
.
5
7
8
3
