The Scientific World Journal / 2012 / Article / Tab 2

Clinical Study

Oral Administration of Polymer Hyaluronic Acid Alleviates Symptoms of Knee Osteoarthritis: A Double-Blind, Placebo-Controlled Study over a 12-Month Period

Table 2

Change of JKOM score during study period.

Time (month)
024612

TotalHA100.0 ± 0.080.6 ± 3.1*71.8 ± 3.0*72.4 ± 3.5*70.9 ± 3.9*
Placebo100.0 ± 0.087.4 ± 3.1*78.9 ± 3.1*74.8 ± 3.2*72.1 ± 4.0*
Subscale
 Pain and stiffness in kneesHA100.0 ± 0.077.0 ± 3.6*70.2 ± 3.7*73.7 ± 4.2*66.8 ± 4.4*
Placebo100.0 ± 0.084.6 ± 4.6*76.5 ± 3.9*71.8 ± 4.0*72.5 ± 8.0*
 Condition in daily lifeHA100.0 ± 0.083.7 ± 3.8*77.6 ± 3.9*77.0 ± 4.1*76.2 ± 4.4*
Placebo100.0 ± 0.089.2 ± 3.7*83.9 ± 4.1*81.3 ± 3.5*76.0 ± 3.4*
 General activitiesHA100.0 ± 0.094.2 ± 7.475.5 ± 4.8*73.3 ± 5.0*81.1 ± 5.8*
Placebo100.0 ± 0.092.5 ± 4.980.3 ± 5.8*73.4 ± 4.8*72.8 ± 4.1*
 Health conditionHA100.0 ± 0.074.0 ± 6.0*#64.6 ± 7.7*#63.0 ± 6.1*#60.9 ± 5.6*#
Placebo100.0 ± 0.096.1 ± 8.291.1 ± 9.988.3 ± 10.1*81.2 ± 6.0*

Results are shown by relative rations (in percent) against scores at baseline. Mean ± SE of 18 (HA group) or 20 (placebo group) subjects are shown.
*P < 0.05 against baseline; #P< 0.05 against placebo group.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.