Research Article

A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of 𝜢 , 𝜢 β€² -Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K 𝟐 C O πŸ‘

Table 2

Comparison of results using K2CO3 with other catalyst for synthesis of 2-amino-4H-pyran-3-carbonitriles.

EntryCatalystSolventTTimeYield (%)Ref

1NaOH/PiperidineEtOHMW5–9 h70-71[17]
2KF-Al2O3DMFRΒ·T10–14 h68–90[18]
3 HTMABH2O110Β°C8 h76–93[19]
4 K2CO3EtOHReflux5–60 min75–95This work