Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome: A Comprehensive Review

Table 2

Drugs implicated in torsades de pointes.

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(1) Antiarrhythmic medications

 Class IA (Quinidine, Procainamide, and Disopyramide)

 Class III (Dofetilide, Ibutilide, Sotalol, and Amiodarone)

 Class IV (Verapamil)

(2) Promotility medications

 Cisapride

(3) Antimicrobial medications

 Macrolides

 Erythromycin

 Clarithromycin

 Fluoroquinolones

 Antiprotozoals

 Pentamidine

 Antimalarials

 Chloroquine

(4) Antipsychotic medications

 Phenothiazine neuroleptics

 Thioridazine

 Chlorpromazine

 Butyrophenone neuroleptics

 Haloperidol

(5) Miscellaneous medications

 Arsenic trioxide

 Methadone

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