Protection of the Extracts of Lentinus edodes Mycelia against Carbon-Tetrachloride-Induced Hepatic Injury in Rats
Figure 2
Effect of LEM on plasma GOT and GPT levels in CCl4-treated rats. (a) Changes of plasma GOT by oral administration of LEM in CCl4-treated rats for 8 weeks. (b) Changes of plasma GPT by oral administration of LEM in CCl4-treated rats for 8 weeks. Lane 1: vehicle-treated Wistar rats; lane 2: vehicle-treated CCl4-induced rats; lane 3: silymarin- (200 mg/kg) treated CCl4-induced rats; lane 4: LEM- (100 mg/kg) treated CCl4-induced rats; lane 5: LEM- (200 mg/kg) treated CCl4-induced rats; lane 6: LEM- (500 mg/kg) treated CCl4-induced rats. Data represent mean ± SEM of eight animals. *, **, and *** compared with CCl4-induced group receiving vehicle.