Clinical Study

Ankle-Brachial Index Is a Powerful Predictor of Renal Outcome and Cardiovascular Events in Patients with Chronic Kidney Disease

Table 4

Cox proportional analysis for cardiovascular events.

ParameterUnivariateMultivariate (forward)
Hazard ratioP valueHazard ratioP value

Age (per 10 years)2.135 (1.356 to 3.364)0.0012.073 (1.297 to 3.311)0.002
Male versus female1.191 (0.521 to 2.719)0.679
Hypertension1.721 (0.528 to 5.613)0.368
Diabetes mellitus1.312 (0.676 to 2.547)0.423
PAOD4.402 (2.230 to 8.691)<0.0013.260 (1.644 to 6.463)0.001
GFR (per 10 ml/min/1.73 m2)0.920 (0.714 to 1.184)0.516
Systolic BP (per 10 mmHg)1.136 (0.976 to 1.323)0.100
Diastolic BP (per 10 mmHg)1.085 (0.805 to 1.463)0.591
Pulse pressure (per 10 mmHg)1.209 (0.988 to 1.480)0.065
BMI (kg/m2)1.016 (0.930 to 1.109)0.726
Albumin (per 1 g/L)0.922 (0.868 to 0.980)0.009
Hb (per 1 g/L)1.005 (0.987 to 1.023)0.607
Cholesterol (per 1 mmol/L)1.098 (0.759 to 1.589)0.620
Uric acid (per 1 μmol/L)1.004 (1.002 to 1.007)0.0011.004 (1.002 to 1.007)0.002
Calcium (per 1 mmol/L)2.669 (0.191 to 37.29)0.466
Phosphate (per 1 mmol/L)1.400 (0.451 to 4.349)0.561
UPCR (per 1 g/g)1.095 (1.010 to 1.186)0.027

PAOD: peripheral arterial occlusive disease, BMI: body mass index, UPCR: urine protein/urine creatinine ratio.