Antioxidants for Preventing Preeclampsia: A Systematic Review

Table 2

Fetal outcomes meta-analysis and heterogeneity results. Comparison: antioxidants versus placebo.

Outcome	Studies	Population size	Pooled RR	95% CI	𝑃 value	Heterogeneity tests
						Chi² 𝑃 value	𝐼^2	Tau²
Preterm birth	13	21,166	1.03	0.94–1.14	0.51	0.05	43.9%	0.01
Small for gestational age <3rd centile	2	11,634	0.85	0.56–1.30	0.46	0.12	57.9%	0.06
Small for gestational age <5th centile	2	5,320	1.06	0.88–1.28	0.54	0.21	37.6%	0.01
Small for gestational age <10th centile	8	9,672	0.92	0.80–1.05	0.22	0.06	49.2%	0.02
Miscarriage or stillbirth	8	9,209	1.17	0.79–1.74	0.44	0.14	35.6%	0.11
Neonatal death	8	19,135	0.79	0.54–1.17	0.24	0.88	0.0%	0.00