Research Article

Serial MRI Features of Canine GM1 Gangliosidosis: A Possible Imaging Biomarker for Diagnosis and Progression of the Disease

Figure 4

Transverse T1W images at the level of the thalamus/3rd ventricle. (a) An age-matched control dog at 2 months of age, (b) an affected laboratory dog at 2 months of age, (c) clinical case (animal 1) at 3 months of age. Symmetrical T1W hyperintensity was found in the internal capsule (arrows) in the affected laboratory dog (b), whereas there was no apparent hyperintensity in animal 1 (c). However, this internal capsule T1W intensity in the affected dog was not higher than that observed in the control dog (a).
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(a)
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(b)
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(c)