The Scientific World Journal / 2012 / Article / Tab 2

Research Article

Morphology of the Myoepithelial Cell: Immunohistochemical Characterization from Resting to Motile Phase

Table 2

Immunohistochemical results for suprabasal and motile myoepithelial cells.

Type of lesionCell morphologyAntibodies for*
p63CK14CK5/6CK19Alpha-SMAVIMER

Normal mammary gland ( 𝑛 = 3 )° Suprabasal resting + + + + + + + + + +
proliferative + + + + + + + + +

Mammary tissue in the same tumor line ( 𝑛 = 2 9 )° Suprabasal resting + + + + + + + + + + + ( 1 2 / 2 9 )
proliferative + + + + + + + + + ( 1 2 / 2 9 )

Benign myoepithelioma ( 𝑛 = 3 )§ Motile spindle ± ( 2 / 3 ) + +
stellate + +

Malignant myoepithelioma ( 𝑛 = 3 )§ Motilespindle ± + +
stellate + +

Carcinoma in benign-mixed tumor ( 𝑛 = 7 )  Suprabasalresting + + + + + ( 5 / 7 ) + + + + + ( 4 / 7 )
proliferative + + + / ± ( 2 / 7 ) + ( 3 / 7 ) + + + + + ( 4 / 7 )
Motilespindle ± ( 2 / 7 ) + ( 3 / 7 ) ± ( 5 / 7 ) + + + ( 3 / 7 )
stellate + + + ( 3 / 7 )

Complex carcinoma ( 𝑛 = 1 6 )  Suprabasalresting + + + + ( 1 5 / 1 6 ) + ( 1 1 / 1 6 ) + + + + + ( 7 / 1 6 )
proliferative + + + ( 1 5 / 1 6 ) + ( 7 / 1 6 ) + + + + + ( 7 / 1 6 )
Motilespindle ± ( 2 / 1 6 ) + ( 7 / 1 6 ) ± ( 5 / 1 6 ) + + + ( 6 / 1 6 )
stellate ± ( 2 / 1 6 ) + + + ( 6 / 1 6 )

*−: no stained cells; ±: less than 5% positive cells; +: 5–50% positive cells; ++: more than 50% positive cells.
°: the motile phonotype is not updated because not present.
§: the suprabasal phonotype is not updated because not detectable around luminal cells.

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