Prevalence of Isolated Atrial Amyloidosis in Young Patients Affected by Congestive Heart Failure
Figure 3
CR and anti-ANP immunostaining of DC heart specimens: CR-IHC-stained paraffin sections from atria of representative DC patients showing atrial amyloid under direct light ((a) and (d)) and polarized light ((b) and (e)). ((c) and (f)) CRF of ANP in the atrial myocardium. (a) Epicardium of a DC patient showing interstitial fibrosis (arrows), loss of nuclei, and myofiber disarray. The image also shows myofibrillar disarray and disruption of sarcomeric architecture. (d) Transmural amyloid deposition reaching through the whole myocardial layer to the endocardial border of a DC patient. Original magnification: (a) 20x, (d) 10x, and (g) 20x.
