Plasma Total Cysteine and Cardiovascular Risk Burden: Action and Interaction

Table 2

Redox characteristics according to risk factors burden.

	All patients (𝑛=304)	Group 0 (𝑛=81)	Group 1 (𝑛=95)	Group 2 (𝑛=80)	Group 3 (𝑛=48)
Plasma total thiols (μm/L)
Homocysteine	9.5 [7.4; 14.1]	9.0 [7.1; 10.9]	9.2 [7.4; 13.8]	11.5 [7.8; 18.6]	9.9 [7.5; 19.0]
Cysteine	250 [210; 291]	228 [197; 269]	253 [203; 280]	260 [223; 305]	280 [230; 320]
Cysteinylglycine	30.8 [23.9; 41.9]	32.7 [24.7; 43.4]	30.2 [24.0; 44.0]	31.1 [23.7; 37.6]	29.9 [22.4; 37.3]
Glutathione	5.5 [4.1; 7.3]	5.9 [4.3; 8.0]	5.6 [4.0; 7.0]	5.4 [4.2; 7.3]	5.5 [3.7; 0.7.5]
Plasma reduced thiols (μm/L)
Homocysteine	0.16 [0.10; 0.24]	0.13 [0.10; 0.21]	0.16 [0.10; 0.24]	0.19 [0.11; 0.29]	0.14 [0.07; 0.28]
Cysteine	7.9 [5.7; 9.4]	7.9 [6.2; 9.0]	7.7 [5.7; 9.1]	7.9 [5.7; 10.0]	8.1 [5.7; 10.1]
Cysteinylglycine	3.3 [2.1; 4.5]	3.5 [2.2; 5.3]	3.5 [2.1; 4.9]	3.3 [2.2; 4.3]	2.9 [1.4; 3.7]
Glutathione	1.9 [1.3; 3.8]	1.9 [1.3; 3.9]	1.8 [1.1; 3.5]	2.1 [1.4; 4.2]	2.1 [1.3; 4.4]
Free malondialdehyde (μmol/L)	0.76 [0.47; 1.35]	0.62 [0.36; 0.89]	0.70 [0.45; 1.30]	0.94 [0.68; 1.33]	1.26 [0.65; 1.49]
Blood reduced glutathione (μmol/L)	655 [496; 824]	655 [451; 821]	705 [536; 859]	663 [454; 842]	569 [499; 771]

Data are expressed as median value and interquartile range [I; III].