LDL-Apheresis: Technical and Clinical Aspects

Table 3

Effectiveness of the various LDL techniques (reduction in percent of original concentration, (according to [1]).

	Cascade filtration (2,500–3,000 mL plasma) reduction of original concentration (%)	Immunoadsorption (4,000–5,000 mL) (%)	Heparin-induced LDL precipitation (HELP) (2,500–3,000 mL) (%)	LDL-adsorption (dextran sulphate) liposorber (2,500–3,000 mL) (%)	LDL hemoperfusion (DALI) 1.6 blood volume (%)	LDL-hemoperfusion (liposorber D) 1.5 blood volume (%)
Cholesterol	35–50	30	50	45	60	55
LDL	30–45	35	45	35–40	60–75	60–75
HDL	35–50	20	10–20	—	16–29	5–13
Lp(A)	60–70	60	46	60	60–75	60–75
Triglycerides	60	60	60	70	ca 40	ca 66
Fibrinogen	50	10–20	50	30	16	20–40
IgM	35	10–20	—	—	21	14
IgA	55	10–20	—	—	—	—
Factor VIII	—	10–20	10–20	20	—	—
C 3	—	—	50	—	—	—
C 4	—	—	50	—	—	—
Plasminogen	—	—	50	—	—	—