Antioxidant Action of Mangrove Polyphenols against Gastric Damage Induced by Absolute Ethanol and Ischemia-Reperfusion in the Rat
Table 2
Effect of RM on the antioxidant compounds and enzymes in ethanol-induced gastric ulcer in rats.
Treatments
Dose (mg kg−1)
GSH (nmol mg of protein−1)
SOD (U mg of protein−1)
Saline
10 (mL kg−1)
5.88 ± 0.379
2.24 ± 1.315
Sham
—
14.58 ± 1.091*
28.82 ± 2.888***
Lansoprazole
30
10.53 ± 0.867
4.29 ± 3.006
RM
0.5
21.44 ± 0.956***
21.87 ± 3.314***
Treatments
Dose (mg kg−1)
GPx (nmol min−1 mg of protein−1)
GR (nmol min−1 mg of protein−1)
Saline
10 (mL kg−1)
50.01 ± 4.248
11.00 ± 1.220
Sham
—
103.8 ± 5.556***
20.56 ± 2.995***
Lansoprazole
30
61.17 ± 4.976
11.26 ± 1.067
RM
0.5
96.66 ± 3.550***
16.94 ± 1.305*
Treatments
Dose (mg kg−1)
LPO (nmol TBARS mg of protein−1)
MPO (U mg of protein−1)
Saline
10 (mL kg−1)
2.98 ± 0.007
2.51 ± 1.013
Sham
—
2.29 ± 0.0280*
1.57 ± 1.730**
Lansoprazole
30
2.47 ± 0.307
1.74 ± 0.233*
RM
0.5
2.14 ± 0.117**
1.75 ± 0.136*
The results are expressed as mean ± s.e.m. (); statistical significance was determined by one-way analysis of variance (ANOVA) followed by Dunnett’s post hoc t test (*, ** and ***).
