Surgical Treatment of Sporadic Pancreatic Neuroendocrine Tumors: A State of the Art Review

Table 1

Tumor-node-metastasis definitions in the European Neuroendocrine Tumor Society (ENETS) for staging for pancreatic neuroendocrine tumors [14, 15].

T—primary tumor
Tx	Primary tumor cannot be assessed
T0	No evidence of primary tumor
T1	Tumor limited to the pancreas and size <2 cm
T2	Tumor limited to the pancreas and size 2–4 cm
T3	Tumor limited to the pancreas and size >4 cm or invading duodenum or bile duct
T4	Tumor invading adjacent organs (stomach, spleen, colon, adrenal gland) or wall of large vessels (celiac axis or superior mesenteric artery)
N—regional lymph nodes
Nx	Regional lymph node cannot be assessed
N0	No regional lymph node metastasis
N1	Regional lymph node metastasis
M—distant metastasis
Mx	Distant metastasis cannot be assessed
M0	No distant metastasis
M1	Distant metastasis