Research Article

Different Modulating Effects of Adenosine on Neonatal and Adult Polymorphonuclear Leukocytes

Figure 4

The modulating effects of adenosine on oxygen radical release of neonatal and adult PMNs. (a) The amount of oxygen free radicals released by PMNs was determined by chemiluminescence. Cord blood PMNs had lower PMA-induced oxygen free radical production than adult PMNs. The results are representative of 6 duplicate experiments. (b) Plots illustrate the relative peak time of oxygen radicals released by adult and cord blood PMNs. The results were normalized to those obtained in pair-controlled studies of adult PMNs with adenosine 0 μM. Data are expressed as mean ± SD. 𝑃 < 0 . 0 5 as compared with adenosine 0 μM. Data presented are calculated from 6 duplicate experiments.
387923.fig.004a
(a)
387923.fig.004b
(b)