Clinical Study

BNP and Admission Glucose as In-Hospital Mortality Predictors in Non-ST Elevation Myocardial Infarction

Table 1

Clinical and demographic patient characteristics, grouped by blood glucose ≥ or < 200 mg/dL.

AllGlucose < 200 mg/dLGlucose ≥ 200 mg/dL 𝑃

Patients, 𝑛 (%)9677 (80.2)19 (19.8)
Age (years)*65.1 (11.7)64.9 (12.0)65.7 (10.7)0.791
Male, 𝑛 (%)64 (66.7)59 (76.6)5 (26.3)<0.001
Prior coronary artery disease, 𝑛 (%)57 (59.4)43 (55.8)14 (73.7)0.156
Hypertension, 𝑛 (%)86 (89.6)67 (87.0)19 (100)0.097
Current smoker, 𝑛 (%)16 (16.7)13 (16.7)3 (15.8)0.909
Dyslipidemia, 𝑛 (%)65 (67.7)53 (68.8)12 (63.2)0.636
Diabetes mellitus, 𝑛 (%)48 (50)30 (38.9)18 (94.7)<0.001
Family history of coronary artery disease, 𝑛 (%)35 (36.5)29 (37.7)6 (31.6)0.622
Heart rate (beats/minute)82.6 (27.6)77.3 (71.9)102.7 (86.4)<0.001
Systolic blood pressure (mmHg)137.5 (30.8)140.2 (29.6)127.8 (33.7)0.121
Diastolic blood pressure (mmHg)83.1 (17.1)84.8 (16.6)76.8 (17.6)0.072
Killip > I, 𝑛 (%)19 (19.8)10 (13.0)9 (47.4)<0.001
Admission glucose (mg/dL)152.4 (100.0)113.1 (31.8)311.9 (122.8)<0.001
BNP (pg/mL)358.3 (381.0)283.7 (339.3)660.8 (399.4)<0.001
Hemoglobin (g/dL)13.5 (2.1)13.9 (1.9)11.8 (2.2)<0.001
White blood cell count (/mm3)9879.6 (3418.4)9437.3 (3181.0)11722.2 (3838.3)0.010
Platelet count (/mm3)235244.7 (82837.8)221118.0 (73987.4)294889.0 (93436.3)<0.001
Serum urea (mg/dL)52.7 (29.4)49.5 (25.9)65.5 (38.6)0.033
Serum creatinine (mg/dL)1.33 (1.00)1.20 (0.48)1.81 (1.98)0.016
Creatinine kinase-MB (CKMB) peak (ng/mL)65.1 (111.1)73.2 (119.5)32.5 (58.7)0.154
Troponin I (ng/mL)25.8 (40.6)26.5 (41.9)23.1 (35.6)0.741
Cholesterol (mg/dL)175.0 (39.4)174.7 (39.7)176.4 (39.3)0.892
HDL-C (mg/dL)41.0 (10.9)40.9 (10.9)41.5 (11.2)0.872
LDL-C (mg/dL)110.6 (32.5)110.0 (32.9)113.4 (321.2)0.732
Triglycerides (mg/dL)130.4 (76.2)129.2 (72.4)136.0 (95.9)0.772
Ejection fraction (%)44.7 (15.3)46.4 (14.3)39.4 (17.4)0.083
Angiography, 𝑛 (%)86 (89.6)72 (93.5)14 (73.7)0.011
Medical therapy, 𝑛 (%)35 (36.5)26 (33.8)9 (47.4)0.270
Percutaneous coronary intervention, 𝑛 (%)49 (57.0)43 (59.7)6 (42.9)0.243
Surgery, 𝑛 (%)12 (12.5)8 (10.4)4 (21.0)0.208
Length of stay (days)10.5 (18.6)7.4 (12.9)22.8 (30.2)<0.001
Followup (months)21.7 (9.7)22.5 (8.7)18.2 (12.8)0.084
Mortality, 𝑛 (%)17 (17.7)11 (14.3)6 (31.6)0.077
 In-hospital, 𝑛 (%)7 (7.3)2 (2.6)5 (26.3)<0.001
 Followup, 𝑛 (%)10 (11.2)9 (12.0)1 (7.1)0.597
In-hospital mortality + prolonged length of stay, 𝑛 (%)25 (26.0)13 (16.9)12 (63.2)<0.001
Follow-up mortality + readmission, 𝑛 (%)51 (57.3)43 (57.3)8 (57.1)0.989