Local Treatment of Hand-Foot Syndrome with Uridine/Thymidine: In Vitro Appraisal on a Human Keratinocyte Cell Line HaCaT

Figure 2

RTCA measurement. Comparison of the protective effect of uridine and thymidine in the presence of 7.5 μg 5-FU/mL. The curves represent the course of HaCaT cell viability after 147 hours of exposure to 5-FU (7.5 μg/mL) only (red curve) or with protective agents: green (5-FU + uridine 50 μg/mL), blue (5-FU thymidine 50 μg/mL). The black curve represents control cells in the culture medium.