Evaluation of Histopathological Changes in Control Biopsies Which Taken 48 Sessions after NBUVB Phototherapy for Early-Stage Mycosis Fungoides

Table 1

Comparison of histopathological changes before and after the treatment.

	Before treatment	After treatment	𝑃
	𝑛 (%)	𝑛 (%)
Epidermotropism
Single/haloed lymphocytes	20 (62.5%)	7 (21.9%)	0.001**
Linearly arranged	30 (93.8%)	6 (18.8%)	0.001**
lymphocytes
Pautrier microabscesses	19 (59.4%)	4 (12.5%)	0.001**
Stratum corneum
Normal	7 (21.9%)	21 (65.6%)	0.004**
Parakeratosis	8 (25.0%)	1 (3.1%)	0.039*
Orthohyperkeratosis	17 (53.1%)	10 (31.3%)	0.143
Epidermis
Normal	9 (28.1%)	15 (46.9%)	0.238
Atrophic	6 (18.8%)	8 (25.0%)	0.791
Hyperplastic	17 (53.1%)	9 (28.1%)	0.134
Inflammatory infiltrates
Superficial, perivascular	—	16 (50.0%)	0.001**
Lichenoid/patchy lichenoid	32 (100%)	7 (21.9%)	0.001**
No inflammation	—	9 (28.1%)	0.004**
Fibrosis
0	6 (18.8%)	6 (18.8%)	1.000
1	22 (68.8%)	22 (68.8%)	1.000
2	3 (9.4%)	3 (9.4%)	1.000
Other changes
Basal vacuolar degeneration	1 (3.1%)	7 (21.9%)	0.070
Dyskeratotic cells	2 (6.3%)	7 (21.9%)	0.180
Melanophages	8 (25.0%)	23 (71.9%)	0.001**
Vascular changes
Telangiectasia	7 (21.9%)	14 (43.8%)	0.118
Vascular proliferation	1 (3.1%)	4 (12.5%)	0.250

Mc Nemar test was used. *P< 0.05, **P< 0.01.