Evaluation of Histopathological Changes in Control Biopsies Which Taken 48 Sessions after NBUVB Phototherapy for Early-Stage Mycosis Fungoides

Table 2

Evaluation of parameters after the treatment, according to response to treatment.

	Response to treatment
After treatment	Yes	No	𝑃
	𝑛 (%)	𝑛 (%)
Epidermotropism
Single/haloed lymphocytes	3 (13.0%)	4 (44.4%)	0.053
Linearly arranged	2 (8.7%)	4 (44.4%)	0.038*
lymphocytes
Pautrier microabscesses	1 (4.3%)	3 (33.3%)	0.057
Stratum corneum
Normal	19 (82.6%)	2 (22.2%)	0.001**
Parakeratosis	0 (0.0%)	1 (11.1%)	0.281
Orthohyperkeratosis	4 (17.4%)	6 (66.7%)	0.007**
Epidermis
Normal	13 (56.5%)	2 (22.2%)	0.122
Atrophic	7 (30.4%)	1 (11.1%)	0.256
Hyperplastic	3 (13.0%)	6 (66.7%)	0.002**
Inflammatory infiltrates
Superficial. perivascular	13 (52.1%)	4 (44.4%)	0.433
Lichenoid/patchy lichenoid	2 (8.7%)	5 (55.6%)	0.004**
No inflammation	9 (39.1%)	0 (0%)	0.027*
Fibrosis
0	6 (26.1%)	0 (0.0%)	0.150
1	15 (65.2%)	7 (77.8%)	0.491
2	1 (4.3%)	2 (22.2%)	0.184
Other changes
Basal vacuolar degeneration	7 (30.4%)	0 (0.0%)	0.061
Dyskeratotic cells	7 (30.4%)	0 (0.0%)	0.061
Melanophages	18 (78.3%)	5 (55.6%)	0.199
Vascular changes
Telangiectasia	10 (43.5%)	4 (44.4%)	0.960
Vascular proliferation	3 (13.0%)	1 (11.1%)	1.000

Chi-square and Fisher's Exact tests were used *P < 0.05, **P< 0.01.