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The Scientific World Journal
Volume 2012 (2012), Article ID 450151, 7 pages
http://dx.doi.org/10.1100/2012/450151
Review Article

Imaging Modalities for the Noninvasive Assessment of Fibrosis in Crohn's Disease

1Department of Internal Medicine, University of Florence, 50134 Florence, Italy
2Department of Clinical Pathophysiology, University of Florence, 50139 Florence, Italy

Received 30 October 2011; Accepted 3 January 2012

Academic Editor: Fabio Fornari

Copyright © 2012 Cristina Stasi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Cosnes, C. Gower-Rousseau, P. Seksik, and A. Cortot, “Epidemiology and natural history of inflammatory bowel diseases,” Gastroenterology, vol. 140, no. 6, pp. 1785–1794, 2011. View at Publisher · View at Google Scholar
  2. S. Ardizzone and G. Bianchi Porro, “Inflammatory bowel disease: new insights into pathogenesis and treatment,” Journal of Internal Medicine, vol. 252, no. 6, pp. 475–496, 2002. View at Publisher · View at Google Scholar · View at Scopus
  3. T. T. Pizarro, L. Pastorelli, G. Bamias et al., “SAMP1/YitFc mouse strain: a spontaneous model of Crohn's disease-like ileitis,” Inflammatory Bowel Diseases, vol. 17, no. 12, pp. 2566–2584, 2011. View at Publisher · View at Google Scholar
  4. L. Peyrin-Biroulet, E. V. Loftus, J. F. Colombel, and W. J. Sandborn, “The natural history of adult crohn's disease in population-based cohorts,” American Journal of Gastroenterology, vol. 105, no. 2, pp. 289–297, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. J. Adler, S. D. Swanson, P. Schmiedlin-Ren et al., “Magnetization transfer helps detect intestinal fibrosis in an animal model of Crohn disease,” Radiology, vol. 259, no. 1, pp. 127–135, 2011. View at Publisher · View at Google Scholar
  6. M. H. Holtmann and M. F. Neurath, “Anti-TNF strategies in stenosing and fistulizing Crohn's disease,” International Journal of Colorectal Disease, vol. 20, no. 1, pp. 1–8, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. S. B. Hanauer, “Bowel ultrasound for the assessment of Crohn’s disease,” Gastroenterol Hepatol, vol. 7, no. 2, pp. 107–109, 2011. View at Google Scholar
  8. C. F. Dietrich, “Significance of abdominal ultrasound in inflammatory bowel disease,” Digestive Diseases, vol. 27, no. 4, pp. 482–493, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Astegiano, F. Bresso, T. Cammarota et al., “Abdominal pain and bowel dysfunction: diagnostic role of intestinal ultrasound,” European Journal of Gastroenterology and Hepatology, vol. 13, no. 8, pp. 927–931, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. F. Parente, S. Greco, M. Molteni et al., “Role of early ultrasound in detecting inflammatory intestinal disorders and identifying their anatomical location within the bowel,” Alimentary Pharmacology and Therapeutics, vol. 18, no. 10, pp. 1009–1016, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. A. S. Borthne, M. Abdelnoor, J. Rugtveit, G. Perminow, T. Reiseter, and N. E. Kløw, “Bowel magnetic resonance imaging of pediatric patients with oral mannitol: MRI compared to endoscopy and intestinal ultrasound,” European Radiology, vol. 16, no. 1, pp. 207–214, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Panés, R. Bouzas, M. Chaparro et al., “Systematic review: the use of ultrasonography, computed tomography and magnetic resonance imaging for the diagnosis, assessment of activity and abdominal complications of Crohn's disease,” Alimentary Pharmacology and Therapeutics, vol. 34, no. 2, pp. 125–145, 2011. View at Publisher · View at Google Scholar
  13. F. Parente, S. Greco, M. Molteni et al., “Oral contrast enhanced bowel ultrasonography in the assessment of small intestine Crohn's disease. A prospective comparison with conventional ultrasound, x ray studies, and ileocolonoscopy,” Gut, vol. 53, no. 11, pp. 1652–1657, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. F. Castiglione, L. Bucci, G. Pesce et al., “Oral contrast-enhanced sonography for the diagnosis and grading of postsurgical recurrence of Crohn's disease,” Inflammatory Bowel Diseases, vol. 14, no. 9, pp. 1240–1245, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Epifanio, M. Baldisserotto, J. V. Spolidoro, and A. Gaiger, “Grey-scale and colour Doppler sonography in the evaluation of children with suspected bowel inflammation: correlation with colonoscopy and histological findings,” Clinical Radiology, vol. 63, no. 9, pp. 968–978, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. B. H. Drews, T. F. E. Barth, M. M. Hänle et al., “Comparison of sonographically measured bowel wall vascularity, histology, and disease activity in Crohn's disease,” European Radiology, vol. 19, no. 6, pp. 1379–1386, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. A. di Sabatino, I. Fulle, R. Ciccocioppo et al., “Doppler enhancement after intravenous Levovist injection in Crohn's disease,” Inflammatory Bowel Diseases, vol. 8, no. 4, pp. 251–257, 2002. View at Google Scholar · View at Scopus
  18. G. L. Rapaccini, M. Pompili, R. Orefice et al., “Contrast-Enhanced Power Doppler of the Intestinal Wall in the Evaluation of Patients with Crohn Disease,” Scandinavian Journal of Gastroenterology, vol. 39, no. 2, pp. 188–194, 2004. View at Publisher · View at Google Scholar · View at Scopus
  19. C. Serra, G. Menozzi, A. M. M. Labate et al., “Ultrasound assessment of vascularization of the thickened terminal ileum wall in Crohn's disease patients using a low-mechanical index real-time scanning technique with a second generation ultrasound contrast agent,” European Journal of Radiology, vol. 62, no. 1, pp. 114–121, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. V. Migaleddu, A. M. Scanu, E. Quaia et al., “Contrast-Enhanced Ultrasonographic Evaluation of Inflammatory Activity in Crohn's Disease,” Gastroenterology, vol. 137, no. 1, pp. 43–52, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. K. Kunihiro, J. Hata, N. Manabe et al., “Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound,” Scandinavian Journal of Gastroenterology, vol. 42, no. 5, pp. 577–585, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. G. Maconi, G. M. Sampietro, A. Sartani, and G. Bianchi Porro, “Bowel ultrasound in Crohn's disease: surgical perspective,” International Journal of Colorectal Disease, vol. 23, no. 4, pp. 339–347, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. W. Kratzer, C. von Tirpitz, R. Mason et al., “Contrast-enhanced power Doppler sonography of the intestinal wall in the differentiation of hypervascularized and hypovascularized intestinal obstructions in patients with Crohn's disease,” Journal of Ultrasound in Medicine, vol. 21, no. 2, pp. 149–157, 2002. View at Google Scholar · View at Scopus
  24. R. W. Stidham, J. Xu, L. A. Johnson et al., “Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and human's with Crohn's disease,” Gastroenterology, vol. 141, no. 3, pp. 819–826.e1, 2011. View at Google Scholar
  25. R. Sinha, P. Murphy, P. Hawker, S. Sanders, A. Rajesh, and R. Verma, “Role of MRI in Crohn's disease,” Clinical Radiology, vol. 64, no. 4, pp. 341–352, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. C. Villa, G. Pompili, G. Franceschelli et al., “Role of magnetic resonance imaging in evaluation of the activity of perianal Crohn's disease,” European Journal of Radiology, vol. 81, no. 4, pp. 616–622, 2012. View at Publisher · View at Google Scholar
  27. A. Kayhan, J. Oommen, F. Dahi, and A. Oto, “Magnetic resonance enterography in Crohn's disease: standard and advanced techniques,” World Journal of Radiology, vol. 2, no. 4, pp. 113–121, 2010. View at Google Scholar
  28. T. C. Lauenstein, H. Schneemann, F. M. Vogt, C. U. Herborn, S. G. Rühm, and J. F. Debatin, “Optimization of oral contrast agents for MR imaging of the small bowel,” Radiology, vol. 228, no. 1, pp. 279–283, 2003. View at Publisher · View at Google Scholar · View at Scopus
  29. N. Gourtsoyiannis, N. Papanikolaou, J. Grammatikakis, T. Maris, and P. Prassopoulos, “MR enteroclysis protocol optimization: comparison between 3D FLASH with fat saturation after intravenous gadolinium injection and true FISP sequences,” European Radiology, vol. 11, no. 6, pp. 908–913, 2001. View at Publisher · View at Google Scholar · View at Scopus
  30. O. A. Kamal and M. M. Shabrawy, “Prognostic role of MRI in determining small bowel Crhon's disease categories: correlation with response to medical therapy,” Egyptian Journal of Radiology and Nuclear Medicine, vol. 42, no. 3-4, pp. 335–342, 2011. View at Publisher · View at Google Scholar
  31. E. Messaris, N. Chandolias, D. Grand, and V. Pricolo, “Role of magnetic resonance enterography in the management of Crohn disease,” Archives of Surgery, vol. 145, no. 5, pp. 471–475, 2010. View at Publisher · View at Google Scholar · View at Scopus
  32. S. Shrot, E. Konen, M. Hertz, and M. Amitai, “Magnetic resonance enterography: 4 years experience in a tertiary medical center,” Israel Medical Association Journal, vol. 13, no. 3, pp. 172–176, 2011. View at Google Scholar
  33. R. del Vescovo, I. Sansoni, R. Caviglia et al., “Dynamic contrast enhanced magnetic resonance imaging of the terminal ileum: differentiation of activity of Crohn's disease,” Abdominal Imaging, vol. 33, no. 4, pp. 417–424, 2008. View at Publisher · View at Google Scholar · View at Scopus
  34. A. Lasocki, A. Pitman, R. Williams, B. Lui, A. V. Kalade, and S. Farish, “Relative efficacy of different MRI signs in diagnosing active Crohn's disease, compared against a histological gold standard,” Journal of Medical Imaging and Radiation Oncology, vol. 55, no. 1, pp. 11–19, 2011. View at Publisher · View at Google Scholar
  35. C. Y. Ha, N. Kumar, C. A. Raptis, V. R. Narra, and M. A. Ciorba, “Magnetic resonance enterography: safe and effective imaging for stricturing Crohn's disease,” Digestive Diseases and Sciences, vol. 56, no. 10, pp. 2906–2913, 2011. View at Publisher · View at Google Scholar
  36. I. C. Lawrance, C. J. Welman, P. Shipman, and K. Murray, “Correlation of MRI-determined small bowel Crohn's disease categories with medical response and surgical pathology,” World Journal of Gastroenterology, vol. 15, no. 27, pp. 3367–3375, 2009. View at Publisher · View at Google Scholar · View at Scopus