Immunohistological Localization of BMP-2, BMP-7, and Their Receptors in Knee Joints with Focal Cartilage Lesions

Table 4

Comparison between patients with different localizations of chondromalacia (retropatellar 𝑛=6 or medial femoral condyle 𝑛=8).

Criterion	Medial femoral condyle	Retropatellar	Significance (P)
Age	30.73 ± 10.85	35.49 ± 12.64	0.6982*
Gender (f/m)	2/3	3/5	0.9999^#
ICRS score	3.75 ± 0.46	3.17 ± 0.41	𝟎.𝟎𝟑𝟕𝟒^∗
Defect size	4.09 ± 1.79	3.29 ± 0.94	0.1882*
KOSS (MRI)	8.12 ± 2.17	5.5 ± 0.87	𝟎.𝟎𝟐𝟎𝟏^∗
Henderson score	2.87 ± 1.36	2.00 ± 0.89	0.1826*
Kellgren-Lawrence score	0.75 ± 0.89	1.00 ± 0.00	0.3838*
Duration of symptoms (months)	65.25 ± 37.84	32.33 ± 21.55	0.0515*
Krenn score	2.25 ± 1.28	2.00 ± 1.26	0.6836*
BMP-2-Syn	2.62 ± 2.26	2.17 ± 1.60	0.9427*
BMP-2-C	2.00 ± 1.19	2.33 ± 2.06	1.000*
BMPR-1A-Syn	5.25 ± 0.89	4.50 ± 0.84	0.1279*
BMPR-1A-C	2.50 ± 2.26	2.50 ± 1.76	0.8860*
Mankin score	8.00 ± 3.34	7.67 ± 0.82	0.8943*
Pritzker score	4.00 ± 1.41	3.17 ± 0.41	0.2810*

^∗𝑈-Test (Mann-Whitney), ^#Fisher exact test, f: female, m: male, Syn: synovia, C: cartilage.